Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 477788..478423 Replicon chromosome
Accession NZ_CP046913
Organism Paraburkholderia acidisoli strain DHF22

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FAZ98_RS02120 Protein ID WP_158948329.1
Coordinates 478106..478423 (-) Length 106 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag FAZ98_RS02115 Protein ID WP_158948327.1
Coordinates 477788..478102 (-) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ98_RS02095 473970..474656 - 687 WP_158948319.1 YafY family transcriptional regulator -
FAZ98_RS02100 474814..475212 - 399 WP_158948321.1 VOC family protein -
FAZ98_RS02105 475470..476288 + 819 WP_158948323.1 glycosyltransferase family 2 protein -
FAZ98_RS02110 476380..477693 - 1314 WP_158948325.1 class I SAM-dependent RNA methyltransferase -
FAZ98_RS02115 477788..478102 - 315 WP_158948327.1 putative addiction module antidote protein Antitoxin
FAZ98_RS02120 478106..478423 - 318 WP_158948329.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAZ98_RS02125 478591..479325 - 735 WP_158948331.1 PqiC family protein -
FAZ98_RS02130 479322..480959 - 1638 WP_158948333.1 MCE family protein -
FAZ98_RS02135 480952..481635 - 684 WP_158948335.1 paraquat-inducible protein A -
FAZ98_RS02140 481789..482709 - 921 WP_158948337.1 paraquat-inducible protein A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-90)

Antitoxin

Uncharacterized protein HI1420

(10-100)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11709.31 Da        Isoelectric Point: 7.2759

>T145151 WP_158948329.1 NZ_CP046913:c478423-478106 [Paraburkholderia acidisoli]
MDYNPHGLTIRTTEVFDTWFVNLSDRIAKRRVQARIDRLMLGNPGDTRSAGAPVIEMRTDHGAGYRVYYVQRGAMLVILL
CGGDKSSQDADIRAAHAMLANLDTE

Download         Length: 318 bp

>T145151 NZ_CP062322:c1164698-1164447 [Staphylococcus aureus]
ATGAATAACCGCGAACAAATAGAACAATCCGTTATAAGTGCTAGTGCGTATAACGGCAATGACACAGAGGGATTACTAAA
AGAGATTGAGGACATATATAAGAAAGCGCAAGCGTTTGATGAAATACTTGAGGGTTTACCTAATGCTATGCAAGATGCAC
TCAAAGAAGATATTTATCTTGATGAAGCAGTAGGGATTATGACGAGTCAAGTGGTCTATAAATATGAGGAGGAGCAGGAA
AATGAGTATTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11056.41 Da        Isoelectric Point: 4.8380

>AT145151 WP_158948327.1 NZ_CP046913:c478102-477788 [Paraburkholderia acidisoli]
MTSSPSQPIATRPWDSAEHLQTEDDIADYFEACLREGGDDPAFIAHALGVIARARGMSEIARETGISREGLYKALSGEVN
PSFGTILKVVKALGLELHGSKASA

Download         Length: 315 bp

>AT145151 NZ_CP062322:c1164457-1164275 [Staphylococcus aureus]
ATGAGTATTAGTGTAGGAGATAAAGTATATAACCATGAAACAAACGAAAGTCTAGAGATTGTGCAATTGGTCGGAGATAT
TAGAGATATACATTACAAGTTATCTGACGGCTCTATTATCAGTCTCATAGACTTTGTTATTAAACCAATTCATTTAATCA
AGGAGGCACAGGAAAATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References