Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 1680024..1680623 Replicon chromosome
Accession NZ_CP046910
Organism Paraburkholderia acidiphila strain 7Q-K02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FAZ97_RS22020 Protein ID WP_158760520.1
Coordinates 1680024..1680320 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FAZ97_RS22025 Protein ID WP_158760521.1
Coordinates 1680324..1680623 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ97_RS22000 1676650..1677423 + 774 WP_158760516.1 TIGR00730 family Rossman fold protein -
FAZ97_RS22005 1677513..1678439 - 927 WP_158760517.1 transcriptional regulator GcvA -
FAZ97_RS22010 1678539..1679144 + 606 WP_158760518.1 chromate transporter -
FAZ97_RS22015 1679141..1679668 + 528 WP_158760519.1 chromate transporter -
FAZ97_RS22020 1680024..1680320 + 297 WP_158760520.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAZ97_RS22025 1680324..1680623 + 300 WP_158760521.1 putative addiction module antidote protein Antitoxin
FAZ97_RS22030 1680670..1682193 - 1524 WP_158760522.1 AMP nucleosidase -
FAZ97_RS22035 1682409..1682816 + 408 WP_158760523.1 hypothetical protein -
FAZ97_RS22040 1682990..1683997 + 1008 WP_158760524.1 homoserine kinase -
FAZ97_RS22045 1683988..1684791 + 804 WP_158760525.1 hypothetical protein -
FAZ97_RS22050 1684898..1685077 - 180 WP_110386165.1 DUF3563 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-97)

Antitoxin

Uncharacterized protein HI1420

(8-91)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11200.84 Da        Isoelectric Point: 10.0224

>T145148 WP_158760520.1 NZ_CP046910:1680024-1680320 [Paraburkholderia acidiphila]
MITLVRSADFDQWLKKLRDARAKARIAARLVSAQHGNFGDYRVLSEGVCEMKIDFGPGYRVYYTRRGTVVYVLLTGGDKS
SQDQDIRRAIQMARELTE

Download         Length: 297 bp

>T145148 NZ_CP062322:20153-20329 [Staphylococcus aureus]
TTGGATAGATGGTGGCTATCTGAGTATAAGGAGGTGGTGCCTATGGTGGCATTACTGAAATCTTTAGAAAGGAGACGCCT
AATGATTACAATTAGTACCATGTTGCAGTTTGGTTTATTCCTTATTGCATTGATAGGTCTAGTAATCAAGCTTATTGAAT
TAAGCAATAAAAAATAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10390.82 Da        Isoelectric Point: 5.0492

>AT145148 WP_158760521.1 NZ_CP046910:1680324-1680623 [Paraburkholderia acidiphila]
MPGTTTYAQFDAADYLDSEETIAEFLAASAEDPNPDVLLAAIAAVARARGMAKVAADAGLGRESLYKALAPGAHPRFETI
QKVLRALGVQTVYKPLGGR

Download         Length: 300 bp

>AT145148 NZ_CP062322:c20491-20317 [Staphylococcus aureus]
ATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCC
GTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGAT
GGTTATTTTTTATTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References