Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3024086..3024605 Replicon chromosome
Accession NZ_CP046909
Organism Paraburkholderia acidiphila strain 7Q-K02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FAZ97_RS13810 Protein ID WP_158758889.1
Coordinates 3024315..3024605 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FAZ97_RS13805 Protein ID WP_158758888.1
Coordinates 3024086..3024328 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ97_RS13785 3019160..3019492 - 333 WP_158758885.1 DUF1778 domain-containing protein -
FAZ97_RS13790 3019777..3020508 - 732 WP_158759173.1 RNA polymerase sigma factor FliA -
FAZ97_RS13795 3020562..3021650 - 1089 WP_158758886.1 MinD/ParA family protein -
FAZ97_RS13800 3021643..3023730 - 2088 WP_158758887.1 flagellar biosynthesis protein FlhF -
FAZ97_RS13805 3024086..3024328 + 243 WP_158758888.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
FAZ97_RS13810 3024315..3024605 + 291 WP_158758889.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAZ97_RS13815 3024672..3026771 - 2100 WP_158758890.1 flagellar biosynthesis protein FlhA -
FAZ97_RS13820 3026768..3028063 - 1296 WP_158758891.1 flagellar type III secretion system protein FlhB -
FAZ97_RS13825 3028300..3029568 - 1269 WP_158758892.1 DUF3443 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11089.03 Da        Isoelectric Point: 10.3672

>T145146 WP_158758889.1 NZ_CP046909:3024315-3024605 [Paraburkholderia acidiphila]
MKTYELKFRETALKEWRQLDSTVRKQFLKKLEERVVTPHVASARLSGMADCYKIKLVASGYRLVYQVVDGELVVLVIAIG
KREADEAYRKARTRLG

Download         Length: 291 bp

>T145146 NZ_CP062320:c2162155-2162048 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8746.07 Da        Isoelectric Point: 4.2346

>AT145146 WP_158758888.1 NZ_CP046909:3024086-3024328 [Paraburkholderia acidiphila]
MESILARASIGISELKVNPMAAIEQADGPVAILNRNKPVAYLVPASEWEAICERLEDAELADIVRSRADEKVLSVKLEDL

Download         Length: 243 bp

>AT145146 NZ_CP062320:2161971-2162031 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References