Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 2203802..2204355 Replicon chromosome
Accession NZ_CP046909
Organism Paraburkholderia acidiphila strain 7Q-K02

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag FAZ97_RS09915 Protein ID WP_158758282.1
Coordinates 2204062..2204355 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FAZ97_RS09910 Protein ID WP_158758281.1
Coordinates 2203802..2204074 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ97_RS09880 2199284..2200720 - 1437 WP_158758277.1 sodium:proton antiporter -
FAZ97_RS09885 2200710..2201372 - 663 WP_158758278.1 lactate utilization protein C -
FAZ97_RS09890 2201454..2202656 - 1203 WP_158758279.1 nicotinate phosphoribosyltransferase -
FAZ97_RS09895 2202983..2203306 + 324 WP_158758280.1 ferredoxin family protein -
FAZ97_RS09910 2203802..2204074 + 273 WP_158758281.1 CopG family ribbon-helix-helix protein Antitoxin
FAZ97_RS09915 2204062..2204355 + 294 WP_158758282.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAZ97_RS09920 2204440..2204916 + 477 WP_158758283.1 CreA family protein -
FAZ97_RS09925 2204945..2205871 + 927 WP_158758284.1 AraC family transcriptional regulator -
FAZ97_RS09930 2206010..2206738 + 729 WP_158759124.1 AzlC family ABC transporter permease -
FAZ97_RS09935 2206735..2207058 + 324 WP_158758285.1 AzlD domain-containing protein -
FAZ97_RS09940 2207193..2207954 + 762 WP_158758286.1 DUF4088 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-40)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10975.54 Da        Isoelectric Point: 7.3575

>T145145 WP_158758282.1 NZ_CP046909:2204062-2204355 [Paraburkholderia acidiphila]
VPRLIVTERAVEGLERCRRFLSRKAPEAARRAAQIISQQLLHLEKTPAIGRPVDGPPELRELVIPFGDSGYVALYLHDTN
DDTVYVLAFRHQHEAGY

Download         Length: 294 bp

>T145145 NZ_CP062320:c2136889-2136623 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10574.67 Da        Isoelectric Point: 5.8461

>AT145145 WP_158758281.1 NZ_CP046909:2203802-2204074 [Paraburkholderia acidiphila]
MATSIKLDEDLKDRVHHIAGLQHRSPHAVMREAIAQYVEREEARERFRQEALASWQHFKETGRHLNGDEVRAWLDSWGTE
DEKSVPECHD

Download         Length: 273 bp

>AT145145 NZ_CP062320:c2137140-2136889 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGTTATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References