Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 787743..788350 Replicon chromosome
Accession NZ_CP046909
Organism Paraburkholderia acidiphila strain 7Q-K02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag FAZ97_RS03530 Protein ID WP_158757217.1
Coordinates 788063..788350 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FAZ97_RS03525 Protein ID WP_158757216.1
Coordinates 787743..788066 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FAZ97_RS03505 783248..784270 + 1023 WP_158757213.1 ABC transporter permease -
FAZ97_RS03510 784373..785341 + 969 WP_158757214.1 substrate-binding domain-containing protein -
FAZ97_RS03515 785356..786405 + 1050 WP_158757215.1 sugar phosphate isomerase/epimerase -
FAZ97_RS03520 786455..787579 + 1125 WP_158759040.1 Gfo/Idh/MocA family oxidoreductase -
FAZ97_RS03525 787743..788066 + 324 WP_158757216.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FAZ97_RS03530 788063..788350 + 288 WP_158757217.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FAZ97_RS03535 788385..789563 - 1179 WP_158757218.1 ABC transporter substrate-binding protein -
FAZ97_RS03540 789650..790591 - 942 WP_028210583.1 CysB family HTH-type transcriptional regulator -
FAZ97_RS03545 790839..792518 + 1680 WP_158757219.1 nitrite/sulfite reductase -
FAZ97_RS03550 792549..793085 + 537 WP_158757220.1 DUF934 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-52)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10960.63 Da        Isoelectric Point: 11.0915

>T145143 WP_158757217.1 NZ_CP046909:788063-788350 [Paraburkholderia acidiphila]
MKVCWSPLALADREATFTFTVTTNPRRAVVWDERISASVRRLRLFPNLGRVGRVSGTRELVVESTPFVLAYRYENEALTI
LRVLHSARRWPDTVD

Download         Length: 288 bp

>T145143 NZ_CP062320:c1814766-1814557 [Staphylococcus aureus]
ATGATACATCAAAATACGATTTACACAGCGGGAATTGAAACAGAAGAACAAGTAAGTCAATTGACAGAACGCATTTCAAA
TATGATAGGTGTTCATCAAGTGAATATTAATATAATAGATGGTCAAGTAACTGTATCGTATGAGACACCAGCAAATTTGA
ATAGTATTGAAAAAGAAATCTATGATGAAGGATACAAAATTGTATTTTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11760.43 Da        Isoelectric Point: 7.4058

>AT145143 WP_158757216.1 NZ_CP046909:787743-788066 [Paraburkholderia acidiphila]
MNANALVQVRIDHALKQRAAEVLDNMGLTVSDAVRILLTRIANEGALPFDFAVDPVAHDAWFRAKVREALEDPRPAVADE
EVEAHFAKRRAAVHGEPGQALKRKAKS

Download         Length: 324 bp

>AT145143 NZ_CP062320:c1815071-1814778 [Staphylococcus aureus]
ATGACTGAACAAGATAATGCACATCATTCTGAACAAATAAAAACGAATCTTAAATCACGTTTAAATCGAATTGAAGGACA
AGTGAGAGCGATTAATCGCATGATTGAAGAAGATGTCTATTGTGATGATGTCCTTACGCAAATAAGAGCGACACGTTCGG
CGTTAAACAGTGTTGCGATAAAGTTATTAGAACAACATATGAAAAGTTGTATTATGAATAAAGTTAATCAAGGTGCTCAG
GAAGAGGCAATGGAAGAGTTATTAGTGACTTTTCAAAAATTGATTAAAGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References