Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 908270..908826 Replicon chromosome
Accession NZ_CP046908
Organism Stappia indica strain PHM037

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GH266_RS04210 Protein ID WP_158192786.1
Coordinates 908270..908575 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GH266_RS04215 Protein ID WP_158192787.1
Coordinates 908572..908826 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GH266_RS04190 903875..905083 + 1209 WP_158192782.1 acetyl-CoA C-acetyltransferase -
GH266_RS04195 905094..906485 + 1392 WP_158192783.1 enoyl-CoA hydratase/isomerase family protein -
GH266_RS04200 906482..907276 + 795 WP_158192784.1 enoyl-CoA hydratase/isomerase family protein -
GH266_RS04205 907311..908249 + 939 WP_158192785.1 nitronate monooxygenase family protein -
GH266_RS04210 908270..908575 - 306 WP_158192786.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GH266_RS04215 908572..908826 - 255 WP_158192787.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GH266_RS04220 908984..909358 - 375 Protein_828 translation initiation factor 2 -
GH266_RS04225 909464..909958 - 495 WP_158192788.1 GNAT family N-acetyltransferase -
GH266_RS04230 910075..910974 - 900 WP_158192789.1 LysR family transcriptional regulator -
GH266_RS04235 911102..912034 + 933 WP_158192790.1 VOC family protein -
GH266_RS04240 912108..912710 + 603 WP_158192791.1 alpha/beta hydrolase -
GH266_RS04245 912741..913457 + 717 WP_158192792.1 pirin-like bicupin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11453.96 Da        Isoelectric Point: 5.5250

>T145142 WP_158192786.1 NZ_CP046908:c908575-908270 [Stappia indica]
VTYRLSARAAEDLIQVYLEGVRLFGEAHAEAYHRDLAAVLELLSENPKLARERGEISPPVRIHPFKAHLVVYVMDEDGGI
LVVRIRHGHEDWAREDWAGGE

Download         Length: 306 bp

>T145142 NZ_CP062320:c1795163-1794801 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9372.49 Da        Isoelectric Point: 6.3191

>AT145142 WP_158192787.1 NZ_CP046908:c908826-908572 [Stappia indica]
MATMNVSLPEQMKAWVEDRARSGRYANASDYVRDLIRRDQERNDRIATMQRLVDEGLASGVSDLNMNGVLEAARARAVKD
TGTS

Download         Length: 255 bp

>AT145142 NZ_CP062320:c1795330-1795160 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References