Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 5737828..5738350 | Replicon | chromosome |
Accession | NZ_CP046874 | ||
Organism | Pseudomonas mediterranea strain S58 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | E3Z27_RS25015 | Protein ID | WP_159286032.1 |
Coordinates | 5738057..5738350 (+) | Length | 98 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A6I6QD85 |
Locus tag | E3Z27_RS25010 | Protein ID | WP_047702740.1 |
Coordinates | 5737828..5738067 (+) | Length | 80 a.a. |
Genomic Context
Location: 5733109..5734446 (1338 bp)
Type: Others
Protein ID: WP_159286031.1
Type: Others
Protein ID: WP_159286031.1
Location: 5734436..5734885 (450 bp)
Type: Others
Protein ID: WP_047702736.1
Type: Others
Protein ID: WP_047702736.1
Location: 5735107..5735727 (621 bp)
Type: Others
Protein ID: WP_047702737.1
Type: Others
Protein ID: WP_047702737.1
Location: 5735727..5736659 (933 bp)
Type: Others
Protein ID: WP_047702738.1
Type: Others
Protein ID: WP_047702738.1
Location: 5737828..5738067 (240 bp)
Type: Antitoxin
Protein ID: WP_047702740.1
Type: Antitoxin
Protein ID: WP_047702740.1
Location: 5738057..5738350 (294 bp)
Type: Toxin
Protein ID: WP_159286032.1
Type: Toxin
Protein ID: WP_159286032.1
Location: 5736720..5737610 (891 bp)
Type: Others
Protein ID: WP_047702739.1
Type: Others
Protein ID: WP_047702739.1
Location: 5738407..5739249 (843 bp)
Type: Others
Protein ID: WP_041021241.1
Type: Others
Protein ID: WP_041021241.1
Location: 5739253..5740872 (1620 bp)
Type: Others
Protein ID: WP_047702742.1
Type: Others
Protein ID: WP_047702742.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
E3Z27_RS24985 | 5733109..5734446 | + | 1338 | WP_159286031.1 | phosphatase PAP2/dual specificity phosphatase family protein | - |
E3Z27_RS24990 | 5734436..5734885 | + | 450 | WP_047702736.1 | hypothetical protein | - |
E3Z27_RS24995 | 5735107..5735727 | + | 621 | WP_047702737.1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase | - |
E3Z27_RS25000 | 5735727..5736659 | + | 933 | WP_047702738.1 | phosphatidate cytidylyltransferase | - |
E3Z27_RS25005 | 5736720..5737610 | - | 891 | WP_047702739.1 | MBL fold metallo-hydrolase | - |
E3Z27_RS25010 | 5737828..5738067 | + | 240 | WP_047702740.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
E3Z27_RS25015 | 5738057..5738350 | + | 294 | WP_159286032.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
E3Z27_RS25020 | 5738407..5739249 | - | 843 | WP_041021241.1 | DUF2135 domain-containing protein | - |
E3Z27_RS25025 | 5739253..5740872 | - | 1620 | WP_047702742.1 | DUF2300 domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 98 a.a. Molecular weight: 11618.43 Da Isoelectric Point: 9.7094
>T145125 WP_159286032.1 NZ_CP046874:5738057-5738350 [Pseudomonas mediterranea]
MTYSLEFDRRALKEWNKLGDTLRQQFKKKLIEVLENPRIEANRLRQLPDCYKLKLRSAGYRLIYQVIDQEVVVFVVAIGK
REREAVYQDVQERISSD
MTYSLEFDRRALKEWNKLGDTLRQQFKKKLIEVLENPRIEANRLRQLPDCYKLKLRSAGYRLIYQVIDQEVVVFVVAIGK
REREAVYQDVQERISSD
Download Length: 294 bp
>T145125 NZ_CP062314:2785097-2785459 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG
Antitoxin
Download Length: 80 a.a. Molecular weight: 8896.21 Da Isoelectric Point: 4.6017
>AT145125 WP_047702740.1 NZ_CP046874:5737828-5738067 [Pseudomonas mediterranea]
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKAALLSEEDEALIAVVTERLSNPQRVKVSLDDL
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKAALLSEEDEALIAVVTERLSNPQRVKVSLDDL
Download Length: 240 bp
>AT145125 NZ_CP062314:2784930-2785100 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6I6QD85 |