Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 5737828..5738350 Replicon chromosome
Accession NZ_CP046874
Organism Pseudomonas mediterranea strain S58

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag E3Z27_RS25015 Protein ID WP_159286032.1
Coordinates 5738057..5738350 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6I6QD85
Locus tag E3Z27_RS25010 Protein ID WP_047702740.1
Coordinates 5737828..5738067 (+) Length 80 a.a.

Genomic Context


E3Z27_RS24985E3Z27_RS24990E3Z27_RS24995E3Z27_RS25000E3Z27_RS25010E3Z27_RS25015E3Z27_RS25005E3Z27_RS25020E3Z27_RS25025
Location: 5733109..5734446 (1338 bp)
Type: Others
Protein ID: WP_159286031.1
Location: 5734436..5734885 (450 bp)
Type: Others
Protein ID: WP_047702736.1
Location: 5735107..5735727 (621 bp)
Type: Others
Protein ID: WP_047702737.1
Location: 5735727..5736659 (933 bp)
Type: Others
Protein ID: WP_047702738.1
Location: 5737828..5738067 (240 bp)
Type: Antitoxin
Protein ID: WP_047702740.1
Location: 5738057..5738350 (294 bp)
Type: Toxin
Protein ID: WP_159286032.1
Location: 5736720..5737610 (891 bp)
Type: Others
Protein ID: WP_047702739.1
Location: 5738407..5739249 (843 bp)
Type: Others
Protein ID: WP_041021241.1
Location: 5739253..5740872 (1620 bp)
Type: Others
Protein ID: WP_047702742.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
E3Z27_RS249855733109..5734446+1338WP_159286031.1phosphatase PAP2/dual specificity phosphatase family protein-
E3Z27_RS249905734436..5734885+450WP_047702736.1hypothetical protein-
E3Z27_RS249955735107..5735727+621WP_047702737.11-acyl-sn-glycerol-3-phosphate acyltransferase-
E3Z27_RS250005735727..5736659+933WP_047702738.1phosphatidate cytidylyltransferase-
E3Z27_RS250055736720..5737610-891WP_047702739.1MBL fold metallo-hydrolase-
E3Z27_RS250105737828..5738067+240WP_047702740.1type II toxin-antitoxin system RelB/DinJ family antitoxinAntitoxin
E3Z27_RS250155738057..5738350+294WP_159286032.1type II toxin-antitoxin system RelE/ParE family toxinToxin
E3Z27_RS250205738407..5739249-843WP_041021241.1DUF2135 domain-containing protein-
E3Z27_RS250255739253..5740872-1620WP_047702742.1DUF2300 domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 11618.43 Da        Isoelectric Point: 9.7094

>T145125 WP_159286032.1 NZ_CP046874:5738057-5738350 [Pseudomonas mediterranea]
MTYSLEFDRRALKEWNKLGDTLRQQFKKKLIEVLENPRIEANRLRQLPDCYKLKLRSAGYRLIYQVIDQEVVVFVVAIGK
REREAVYQDVQERISSD

Download         Length: 294 bp

>T145125 NZ_CP062314:2785097-2785459 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAGTTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8896.21 Da        Isoelectric Point: 4.6017

>AT145125 WP_047702740.1 NZ_CP046874:5737828-5738067 [Pseudomonas mediterranea]
MASINIRIDDDLKQRSFAELEKLGVTPSELLRQTLQYVAERGKLPFKAALLSEEDEALIAVVTERLSNPQRVKVSLDDL

Download         Length: 240 bp

>AT145125 NZ_CP062314:2784930-2785100 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
AlphaFold DBA0A6I6QD85

References