Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1642139..1642683 Replicon chromosome
Accession NZ_CP046857
Organism Vibrio fluvialis strain 2015AW-0233

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GO174_RS07580 Protein ID WP_158125210.1
Coordinates 1642139..1642438 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GO174_RS07585 Protein ID WP_158125211.1
Coordinates 1642426..1642683 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GO174_RS07550 1637837..1638829 + 993 WP_020329950.1 OmpA family protein -
GO174_RS07555 1638904..1639191 + 288 WP_024373222.1 hypothetical protein -
GO174_RS07560 1639328..1639855 + 528 WP_020329948.1 copper resistance protein NlpE -
GO174_RS07565 1639933..1640766 - 834 WP_158125208.1 SDR family oxidoreductase -
GO174_RS07570 1640920..1641291 + 372 WP_024373224.1 helix-turn-helix transcriptional regulator -
GO174_RS07575 1641486..1641761 + 276 WP_158125209.1 D-fructose-6-phosphate amidotransferase -
GO174_RS07580 1642139..1642438 - 300 WP_158125210.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GO174_RS07585 1642426..1642683 - 258 WP_158125211.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GO174_RS07590 1642831..1643307 - 477 WP_158125212.1 sensor protein -
GO174_RS07600 1643472..1643915 - 444 WP_041942512.1 hypothetical protein -
GO174_RS07605 1644401..1645441 - 1041 WP_020329939.1 hypothetical protein -
GO174_RS07610 1645453..1646352 - 900 WP_004725079.1 flagellar hook-associated protein FlgL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11415.30 Da        Isoelectric Point: 4.8604

>T145115 WP_158125210.1 NZ_CP046857:c1642438-1642139 [Vibrio fluvialis]
MAEIIWTEPALSDLNDIAEYIALENVAAAKQLVQTIFAKVERLENFPESGRIPPELAHLSYRELVVNPCRIFYKSDGDKV
FILFVMRSERDLRKFLLGM

Download         Length: 300 bp

>T145115 NZ_CP062312:2722711-2723073 [Staphylococcus aureus]
ATGATTAGACGAGGAGATGTTTATTTAGCAGATTTATCACCAGTACAGGGATCTGAACAAGGGGGAGTCAGACCTGTAGT
CATAATTCAAAATGATACTGGTAATAAATATAGTCCTACAGTTATTGTTGCGGCAATAACTGGTAGGATTAATAAAGCGA
AAATACCGACACATGTAGAGATTGAAAAGAAAAAGTATAAATTGGATAAAGACTCAGTTATATTATTAGAACAAATTCGT
ACACTTGATAAAAAACGATTGAAAGAAAAACTGACGTACTTATCCGATGATAAAATGAAAGAAGTAGATAATGCACTAAT
GATTAGTTTAGGGCTGAATGCAGTAGCTCACCAGAAAAATTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9689.23 Da        Isoelectric Point: 8.5255

>AT145115 WP_158125211.1 NZ_CP046857:c1642683-1642426 [Vibrio fluvialis]
MKVELVTSLKRQATKILADLRSTKEPVLITEHGKPSAYLVDVEDYEFMQNRLTILEGIARGERAFADGKVVSHEEAKDKM
SKWLK

Download         Length: 258 bp

>AT145115 NZ_CP062312:2722544-2722714 [Staphylococcus aureus]
ATGTTATCTTTTAGTCAAAATAGAAGTCATAGCTTAGAACAATCTTTAAAAGAAGGATATTCACAAATGGCTGATTTAAA
TCTCTCCCTAGCGAACGAAGCTTTTCCGATAGAGTGTGAAGCATGCGATTGCAACGAAACATATTTATCTTCTAATTCAA
CGAATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References