Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | parDE/ParE-RHH |
| Location | 1297662..1298200 | Replicon | chromosome |
| Accession | NZ_CP046835 | ||
| Organism | Vibrio vulnificus strain 07-2444 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | GPY41_RS14005 | Protein ID | WP_017420621.1 |
| Coordinates | 1297901..1298200 (+) | Length | 100 a.a. |
Antitoxin (Protein)
| Gene name | parD | Uniprot ID | A0A0F2HR74 |
| Locus tag | GPY41_RS14000 | Protein ID | WP_011080384.1 |
| Coordinates | 1297662..1297904 (+) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GPY41_RS13945 | 1292939..1293370 | - | 432 | WP_158123477.1 | NUDIX domain-containing protein | - |
| GPY41_RS13950 | 1293528..1294076 | - | 549 | WP_158123478.1 | hypothetical protein | - |
| GPY41_RS13955 | 1294111..1294203 | - | 93 | WP_158123479.1 | DUF3265 domain-containing protein | - |
| GPY41_RS13960 | 1294225..1294800 | - | 576 | WP_081384157.1 | hypothetical protein | - |
| GPY41_RS13965 | 1294851..1294943 | - | 93 | WP_005531022.1 | DUF3265 domain-containing protein | - |
| GPY41_RS13970 | 1294958..1295368 | - | 411 | WP_045612970.1 | cytidine deaminase | - |
| GPY41_RS13975 | 1295387..1295521 | - | 135 | WP_158124224.1 | DUF3265 domain-containing protein | - |
| GPY41_RS13980 | 1295993..1296400 | - | 408 | WP_158123425.1 | hypothetical protein | - |
| GPY41_RS13985 | 1296360..1296557 | - | 198 | WP_158123480.1 | DUF3265 domain-containing protein | - |
| GPY41_RS13990 | 1296896..1297024 | - | 129 | WP_158124225.1 | DUF3265 domain-containing protein | - |
| GPY41_RS13995 | 1297021..1297476 | - | 456 | WP_038964950.1 | GNAT family N-acetyltransferase | - |
| GPY41_RS14000 | 1297662..1297904 | + | 243 | WP_011080384.1 | type II toxin-antitoxin system ParD family antitoxin | Antitoxin |
| GPY41_RS14005 | 1297901..1298200 | + | 300 | WP_017420621.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| GPY41_RS14010 | 1298522..1298974 | + | 453 | WP_158123481.1 | hypothetical protein | - |
| GPY41_RS14015 | 1299000..1299131 | - | 132 | WP_199252254.1 | DUF3265 domain-containing protein | - |
| GPY41_RS14020 | 1299468..1299596 | - | 129 | WP_158124226.1 | DUF3265 domain-containing protein | - |
| GPY41_RS14025 | 1299603..1300013 | - | 411 | WP_158123482.1 | hypothetical protein | - |
| GPY41_RS14030 | 1300150..1300737 | - | 588 | WP_158123483.1 | hypothetical protein | - |
| GPY41_RS14035 | 1300721..1300843 | - | 123 | WP_158123484.1 | DUF3265 domain-containing protein | - |
| GPY41_RS14040 | 1300891..1301412 | - | 522 | WP_158123485.1 | hypothetical protein | - |
| GPY41_RS14045 | 1301491..1302030 | - | 540 | WP_080538379.1 | hypothetical protein | - |
| GPY41_RS14050 | 1302030..1302170 | - | 141 | WP_158124227.1 | DUF3265 domain-containing protein | - |
| GPY41_RS14055 | 1302531..1302623 | - | 93 | WP_072605894.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 1150341..1350499 | 200158 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 100 a.a. Molecular weight: 11669.37 Da Isoelectric Point: 9.9572
>T145039 WP_017420621.1 NZ_CP046835:1297901-1298200 [Vibrio vulnificus]
MRPFQLTNKAKSDLRDIALFTSRRWGREQRNIYLKQFDDSFWLLAENPDIGKACDEIRDGYRKFPQGSHVIFYRQIGSQN
IEIIRILHKSMDVNPILGA
MRPFQLTNKAKSDLRDIALFTSRRWGREQRNIYLKQFDDSFWLLAENPDIGKACDEIRDGYRKFPQGSHVIFYRQIGSQN
IEIIRILHKSMDVNPILGA
Download Length: 300 bp
>T145039 NZ_CP062250:c3034182-3033775 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8953.88 Da Isoelectric Point: 4.2213
>AT145039 WP_011080384.1 NZ_CP046835:1297662-1297904 [Vibrio vulnificus]
MAKNTSITLGDHFDGFIANQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGVADYDLDSFINELDSEERK
MAKNTSITLGDHFDGFIANQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGVADYDLDSFINELDSEERK
Download Length: 243 bp
>AT145039 NZ_CP062250:c3034429-3034163 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|