Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/YafN(antitoxin) |
| Location | 1536124..1536689 | Replicon | chromosome |
| Accession | NZ_CP046828 | ||
| Organism | Vibrio parahaemolyticus strain 2010V-1106 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | A0A249W588 |
| Locus tag | GPY32_RS16295 | Protein ID | WP_023667331.1 |
| Coordinates | 1536402..1536689 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | GPY32_RS16290 | Protein ID | WP_023667330.1 |
| Coordinates | 1536124..1536405 (+) | Length | 94 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GPY32_RS16245 | 1531834..1532418 | + | 585 | WP_029850554.1 | hypothetical protein | - |
| GPY32_RS16250 | 1532433..1532525 | + | 93 | WP_079748814.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16255 | 1532572..1532928 | + | 357 | WP_021485171.1 | hypothetical protein | - |
| GPY32_RS16260 | 1532952..1533041 | + | 90 | WP_079748783.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16265 | 1533069..1533650 | + | 582 | WP_023667325.1 | putative mannitol operon repressor domain protein | - |
| GPY32_RS16275 | 1534867..1535283 | + | 417 | WP_023667328.1 | VOC family protein | - |
| GPY32_RS16280 | 1535317..1535394 | + | 78 | WP_079748784.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16285 | 1535423..1535914 | + | 492 | WP_029850189.1 | hypothetical protein | - |
| GPY32_RS16290 | 1536124..1536405 | + | 282 | WP_023667330.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| GPY32_RS16295 | 1536402..1536689 | + | 288 | WP_023667331.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| GPY32_RS16300 | 1536692..1536808 | + | 117 | WP_078532102.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16310 | 1537289..1537420 | + | 132 | WP_005494795.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16315 | 1538431..1538553 | + | 123 | WP_079748760.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16320 | 1538572..1539039 | + | 468 | WP_005494803.1 | GNAT family N-acetyltransferase | - |
| GPY32_RS16325 | 1539039..1539167 | + | 129 | WP_161612914.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16330 | 1539530..1539622 | + | 93 | WP_005494807.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16335 | 1539724..1539933 | + | 210 | WP_025506672.1 | DUF3955 domain-containing protein | - |
| GPY32_RS16345 | 1540607..1540696 | + | 90 | WP_078235921.1 | DUF3265 domain-containing protein | - |
| GPY32_RS16350 | 1540730..1541182 | + | 453 | WP_005494814.1 | hypothetical protein | - |
| GPY32_RS16355 | 1541218..1541310 | + | 93 | WP_078535095.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1520228..1609933 | 89705 | |
| - | inside | Integron | - | - | 1520752..1609252 | 88500 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10949.53 Da Isoelectric Point: 5.0980
>T145021 WP_023667331.1 NZ_CP046828:1536402-1536689 [Vibrio parahaemolyticus]
MKVVWSPLALQKLGDAAEFISLDNPSAAEKWVNDVFDKTESLGSMPEMGRFVPEIPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILTEDDV
MKVVWSPLALQKLGDAAEFISLDNPSAAEKWVNDVFDKTESLGSMPEMGRFVPEIPHTNYREIIFGHYRIIYSLSHEIRV
LTVRNCRQILTEDDV
Download Length: 288 bp
>T145021 NZ_CP062250:c242726-242448 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
ATGATTCAAAGGGATATTGAATACTCGGGACAATATTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATACTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10427.94 Da Isoelectric Point: 5.1991
>AT145021 WP_023667330.1 NZ_CP046828:1536124-1536405 [Vibrio parahaemolyticus]
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
EEARAEVLGRIKK
MSRIHFDQDIQPLSEFRAGVASYIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLASGLGVSN
EEARAEVLGRIKK
Download Length: 282 bp
>AT145021 NZ_CP062250:c242989-242729 [Escherichia coli]
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
ATGGCTGCTAACGCGTTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCAGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCATTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|