Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-RelB |
Location | 56544..57103 | Replicon | chromosome |
Accession | NZ_CP046819 | ||
Organism | Vibrio metoecus strain 2011V-1015 |
Toxin (Protein)
Gene name | relE | Uniprot ID | D7HHK2 |
Locus tag | GPY06_RS00260 | Protein ID | WP_000578471.1 |
Coordinates | 56825..57103 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | GPY06_RS00255 | Protein ID | WP_019829633.1 |
Coordinates | 56544..56828 (+) | Length | 95 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
GPY06_RS00225 | 51894..53071 | + | 1178 | WP_165481032.1 | IS3 family transposase | - |
GPY06_RS00230 | 53082..53540 | - | 459 | Protein_45 | hypothetical protein | - |
GPY06_RS00235 | 53691..53936 | + | 246 | WP_001260801.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
GPY06_RS00240 | 53936..54253 | + | 318 | WP_095474062.1 | CcdB family protein | - |
GPY06_RS00245 | 54469..55428 | + | 960 | WP_158118895.1 | IS30 family transposase | - |
GPY06_RS00250 | 55755..56336 | - | 582 | WP_158118896.1 | hypothetical protein | - |
GPY06_RS00255 | 56544..56828 | + | 285 | WP_019829633.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
GPY06_RS00260 | 56825..57103 | + | 279 | WP_000578471.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
GPY06_RS00265 | 57302..57484 | - | 183 | WP_158118897.1 | DUF645 family protein | - |
GPY06_RS00270 | 57793..58080 | - | 288 | WP_000869999.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
GPY06_RS00275 | 58077..58358 | - | 282 | WP_000086649.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
GPY06_RS00280 | 58573..58962 | - | 390 | WP_000491261.1 | VOC family protein | - |
GPY06_RS00285 | 59177..59554 | - | 378 | WP_158118899.1 | hypothetical protein | - |
GPY06_RS00290 | 59718..60314 | - | 597 | WP_158118900.1 | hypothetical protein | - |
GPY06_RS00295 | 60567..60704 | - | 138 | WP_158118901.1 | DUF645 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integron | - | - | 51554..166505 | 114951 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10838.56 Da Isoelectric Point: 4.6794
>T144997 WP_000578471.1 NZ_CP046819:56825-57103 [Vibrio metoecus]
MIFWEEASLNDREKIFEFLYDFNPAAAEKTDELIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSKIRIM
RVLHQKQKFPND
MIFWEEASLNDREKIFEFLYDFNPAAAEKTDELIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVDGSKIRIM
RVLHQKQKFPND
Download Length: 279 bp
>T144997 NZ_CP062249:c475764-475546 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA
Antitoxin
Download Length: 95 a.a. Molecular weight: 10929.30 Da Isoelectric Point: 8.0775
>AT144997 WP_019829633.1 NZ_CP046819:56544-56828 [Vibrio metoecus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNQAFEKFDSGKAVFIEHDIVKAR
MAERKAKIRNRGHA
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQVNQAFEKFDSGKAVFIEHDIVKAR
MAERKAKIRNRGHA
Download Length: 285 bp
>AT144997 NZ_CP062249:c476164-475790 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTAAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|