Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 1050088..1050635 Replicon chromosome
Accession NZ_CP046818
Organism Vibrio metoecus strain 06-2478

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPX95_RS17890 Protein ID WP_158160340.1
Coordinates 1050333..1050635 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GPX95_RS17885 Protein ID WP_012518671.1
Coordinates 1050088..1050345 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPX95_RS17840 1045142..1045399 + 258 WP_055031549.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GPX95_RS17845 1045387..1045689 + 303 WP_055031550.1 type II toxin-antitoxin system RelE/ParE family toxin -
GPX95_RS17850 1045866..1046618 + 753 WP_055031551.1 SDR family oxidoreductase -
GPX95_RS17855 1046921..1047103 + 183 WP_055031552.1 DUF645 family protein -
GPX95_RS17860 1047447..1047629 + 183 WP_055031561.1 DUF645 family protein -
GPX95_RS17865 1047838..1048275 + 438 WP_158003313.1 hypothetical protein -
GPX95_RS17870 1048421..1048846 + 426 WP_000405023.1 GNAT family N-acetyltransferase -
GPX95_RS17875 1048983..1049498 + 516 WP_001894921.1 lipocalin family protein -
GPX95_RS17885 1050088..1050345 + 258 WP_012518671.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GPX95_RS17890 1050333..1050635 + 303 WP_158160340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GPX95_RS17895 1050821..1052077 + 1257 WP_000273667.1 AAA family ATPase -
GPX95_RS17900 1052061..1052642 + 582 WP_000594092.1 HNH endonuclease -
GPX95_RS17910 1052790..1053830 + 1041 WP_134981118.1 hypothetical protein -
GPX95_RS17915 1053978..1054514 + 537 WP_158160341.1 nucleotidyltransferase family protein -
GPX95_RS17920 1054660..1055382 - 723 WP_032477470.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
GPX95_RS17925 1055384..1055596 - 213 WP_000526880.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1024742..1129239 104497
- inside Integron - - 1025906..1128911 103005


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11765.72 Da        Isoelectric Point: 5.1972

>T144992 WP_158160340.1 NZ_CP046818:1050333-1050635 [Vibrio metoecus]
MVEIIWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVNPCRVFYKYDDAKV
RILFVMRVERDLRRLMLTKQ

Download         Length: 303 bp

>T144992 NZ_CP062248:c4523871-4523614 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9661.18 Da        Isoelectric Point: 7.3180

>AT144992 WP_012518671.1 NZ_CP046818:1050088-1050345 [Vibrio metoecus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVEDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDRM
SKWLK

Download         Length: 258 bp

>AT144992 NZ_CP062248:c4523602-4523057 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References