Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-Phd
Location 1045142..1045689 Replicon chromosome
Accession NZ_CP046818
Organism Vibrio metoecus strain 06-2478

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPX95_RS17845 Protein ID WP_055031550.1
Coordinates 1045387..1045689 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GPX95_RS17840 Protein ID WP_055031549.1
Coordinates 1045142..1045399 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPX95_RS17790 1040496..1040759 + 264 WP_055031542.1 hypothetical protein -
GPX95_RS17795 1040790..1040882 + 93 WP_198926207.1 DUF3265 domain-containing protein -
GPX95_RS17800 1041078..1041248 + 171 WP_158160363.1 DUF645 family protein -
GPX95_RS17805 1041450..1041968 + 519 WP_055031543.1 GNAT family N-acetyltransferase -
GPX95_RS17810 1042208..1042435 + 228 WP_055031544.1 hypothetical protein -
GPX95_RS17815 1042745..1042927 + 183 WP_158160364.1 DUF645 family protein -
GPX95_RS17820 1043127..1043495 + 369 WP_055031546.1 hypothetical protein -
GPX95_RS17825 1043663..1044079 + 417 WP_055031547.1 hypothetical protein -
GPX95_RS17830 1044081..1044374 + 294 WP_055031548.1 hypothetical protein -
GPX95_RS17835 1044447..1044944 + 498 WP_029857382.1 DinB family protein -
GPX95_RS17840 1045142..1045399 + 258 WP_055031549.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GPX95_RS17845 1045387..1045689 + 303 WP_055031550.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GPX95_RS17850 1045866..1046618 + 753 WP_055031551.1 SDR family oxidoreductase -
GPX95_RS17855 1046921..1047103 + 183 WP_055031552.1 DUF645 family protein -
GPX95_RS17860 1047447..1047629 + 183 WP_055031561.1 DUF645 family protein -
GPX95_RS17865 1047838..1048275 + 438 WP_158003313.1 hypothetical protein -
GPX95_RS17870 1048421..1048846 + 426 WP_000405023.1 GNAT family N-acetyltransferase -
GPX95_RS17875 1048983..1049498 + 516 WP_001894921.1 lipocalin family protein -
GPX95_RS17885 1050088..1050345 + 258 WP_012518671.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GPX95_RS17890 1050333..1050635 + 303 WP_158160340.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1024742..1129239 104497
- inside Integron - - 1025906..1128911 103005


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-69)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11681.51 Da        Isoelectric Point: 4.8838

>T144991 WP_055031550.1 NZ_CP046818:1045387-1045689 [Vibrio metoecus]
MAEIVWTEPALSDLNDIAEYIALENVVAAKQLVQTVFTKVERLADFPESGRVPPELEHLNYREVVVNPCRVFYKYDDANV
RILFVMRAERDLRRLMLTKQ

Download         Length: 303 bp

>T144991 NZ_CP062248:4438510-4438860 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACACGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9619.14 Da        Isoelectric Point: 7.3176

>AT144991 WP_055031549.1 NZ_CP046818:1045142-1045399 [Vibrio metoecus]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLIDVDDYEFMQNRLAILEGIARGERALADGKVVSHQDAKDKM
SKWLK

Download         Length: 258 bp

>AT144991 NZ_CP062248:4438265-4438516 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References