Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 73548..74107 Replicon chromosome
Accession NZ_CP046812
Organism Vibrio alginolyticus strain 2010V-1102

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPY28_RS00400 Protein ID WP_053307293.1
Coordinates 73548..73826 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GPY28_RS00405 Protein ID WP_053307294.1
Coordinates 73823..74107 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPY28_RS00360 69581..70216 + 636 WP_053307288.1 hypothetical protein -
GPY28_RS00365 70459..70749 - 291 WP_053307289.1 type II toxin-antitoxin system RelE/ParE family toxin -
GPY28_RS00370 70739..70987 - 249 WP_005377003.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
GPY28_RS00375 71062..71154 + 93 WP_196334432.1 DUF3265 domain-containing protein -
GPY28_RS00380 71185..71832 + 648 WP_053307290.1 DUF4263 domain-containing protein -
GPY28_RS00385 71976..72473 - 498 WP_053307291.1 GNAT family N-acetyltransferase -
GPY28_RS00390 72470..72742 - 273 WP_013571703.1 DUF1778 domain-containing protein -
GPY28_RS00395 72976..73428 + 453 WP_053307292.1 hypothetical protein -
GPY28_RS00400 73548..73826 - 279 WP_053307293.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
GPY28_RS00405 73823..74107 - 285 WP_053307294.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GPY28_RS00410 74184..74276 + 93 WP_196334436.1 DUF3265 domain-containing protein -
GPY28_RS00415 74797..74886 + 90 WP_080996190.1 DUF3265 domain-containing protein -
GPY28_RS00420 75252..75731 + 480 WP_053307295.1 DUF1456 family protein -
GPY28_RS00430 76477..77199 - 723 WP_199266780.1 Crp/Fnr family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10935.69 Da        Isoelectric Point: 4.3430

>T144978 WP_053307293.1 NZ_CP046812:c73826-73548 [Vibrio alginolyticus]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLDQPLMGVQRDGVRGRLLIIPEISMIVSYWIEGEIIRIM
RVLHQKQKFPMD

Download         Length: 279 bp

>T144978 NZ_CP062248:c1917465-1917362 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11145.50 Da        Isoelectric Point: 9.0980

>AT144978 WP_053307294.1 NZ_CP046812:c74107-73823 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLYHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp

>AT144978 NZ_CP062248:1917324-1917595 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References