Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 70459..70987 Replicon chromosome
Accession NZ_CP046812
Organism Vibrio alginolyticus strain 2010V-1102

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPY28_RS00365 Protein ID WP_053307289.1
Coordinates 70459..70749 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR02
Locus tag GPY28_RS00370 Protein ID WP_005377003.1
Coordinates 70739..70987 (-) Length 83 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPY28_RS00340 65696..66466 - 771 WP_053307368.1 hypothetical protein -
GPY28_RS00345 66463..67440 - 978 WP_053307369.1 hypothetical protein -
GPY28_RS00350 67433..68194 - 762 WP_053307370.1 hypothetical protein -
GPY28_RS00355 68197..68736 - 540 WP_053307371.1 hypothetical protein -
GPY28_RS00360 69581..70216 + 636 WP_053307288.1 hypothetical protein -
GPY28_RS00365 70459..70749 - 291 WP_053307289.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GPY28_RS00370 70739..70987 - 249 WP_005377003.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GPY28_RS00375 71062..71154 + 93 WP_196334432.1 DUF3265 domain-containing protein -
GPY28_RS00380 71185..71832 + 648 WP_053307290.1 DUF4263 domain-containing protein -
GPY28_RS00385 71976..72473 - 498 WP_053307291.1 GNAT family N-acetyltransferase -
GPY28_RS00390 72470..72742 - 273 WP_013571703.1 DUF1778 domain-containing protein -
GPY28_RS00395 72976..73428 + 453 WP_053307292.1 hypothetical protein -
GPY28_RS00400 73548..73826 - 279 WP_053307293.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
GPY28_RS00405 73823..74107 - 285 WP_053307294.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
GPY28_RS00410 74184..74276 + 93 WP_196334436.1 DUF3265 domain-containing protein -
GPY28_RS00415 74797..74886 + 90 WP_080996190.1 DUF3265 domain-containing protein -
GPY28_RS00420 75252..75731 + 480 WP_053307295.1 DUF1456 family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11276.27 Da        Isoelectric Point: 10.6284

>T144976 WP_053307289.1 NZ_CP046812:c70749-70459 [Vibrio alginolyticus]
MTYRLDFKKSALKEWKKLGSTLQQQFKKKLIERLDSPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDIIIVTVLAVGK
RERSDVYRKAMKRLDD

Download         Length: 291 bp

>T144976 NZ_CP062248:c1586433-1585111 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCAAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCCAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTGACGTTAATACCCGAAGA
CGAAACCGTAACGCATCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGACTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCGCTAGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCACAGGAGAAGACAGCACTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCA
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAAGCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9079.37 Da        Isoelectric Point: 3.9610

>AT144976 WP_005377003.1 NZ_CP046812:c70987-70739 [Vibrio alginolyticus]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp

>AT144976 NZ_CP062248:c1586699-1586433 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACGCGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAAATCTGGAGTGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A347UR02

References