Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1294183..1294681 Replicon chromosome
Accession NZ_CP046804
Organism Vibrio cidicii strain 2756-81

Toxin (Protein)


Gene name - Uniprot ID A0A151JG87
Locus tag GPY24_RS12090 Protein ID WP_000589153.1
Coordinates 1294415..1294681 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A151JFU0
Locus tag GPY24_RS12085 Protein ID WP_000643599.1
Coordinates 1294183..1294428 (-) Length 82 a.a.

Genomic Context

GPY24_RS12040GPY24_RS12045GPY24_RS12050GPY24_RS12055GPY24_RS12060GPY24_RS12065GPY24_RS12070GPY24_RS12075GPY24_RS12080GPY24_RS12085GPY24_RS12090GPY24_RS12095GPY24_RS12100GPY24_RS12105GPY24_RS12110GPY24_RS12115GPY24_RS12120GPY24_RS12125GPY24_RS12130
Location: 1289186..1289311 (126 bp)
Type: Others
Protein ID: WP_082796158.1
Location: 1289293..1289772 (480 bp)
Type: Others
Protein ID: WP_065818787.1
Location: 1289917..1290873 (957 bp)
Type: Others
Protein ID: WP_197467496.1
Location: 1290930..1291463 (534 bp)
Type: Others
Protein ID: WP_065818788.1
Location: 1291614..1292009 (396 bp)
Type: Others
Protein ID: WP_000870857.1
Location: 1292165..1293040 (876 bp)
Type: Others
Protein ID: WP_065818789.1
Location: 1293070..1293159 (90 bp)
Type: Others
Protein ID: WP_084834173.1
Location: 1293176..1293574 (399 bp)
Type: Others
Protein ID: WP_156478402.1
Location: 1293602..1293727 (126 bp)
Type: Others
Protein ID: Protein_1209
Location: 1294183..1294428 (246 bp)
Type: Antitoxin
Protein ID: WP_000643599.1
Location: 1294415..1294681 (267 bp)
Type: Toxin
Protein ID: WP_000589153.1
Location: 1294858..1295322 (465 bp)
Type: Others
Protein ID: WP_158118642.1
Location: 1295440..1295733 (294 bp)
Type: Others
Protein ID: WP_158118643.1
Location: 1295721..1295813 (93 bp)
Type: Others
Protein ID: WP_156478403.1
Location: 1295870..1296145 (276 bp)
Type: Others
Protein ID: WP_065819779.1
Location: 1296185..1296334 (150 bp)
Type: Others
Protein ID: WP_080478972.1
Location: 1296292..1296576 (285 bp)
Type: Others
Protein ID: Protein_1217
Location: 1296696..1297397 (702 bp)
Type: Others
Protein ID: WP_197467433.1
Location: 1297408..1298940 (1533 bp)
Type: Others
Protein ID: WP_065818814.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GPY24_RS120401289186..1289311-126WP_082796158.1DUF3265 domain-containing protein-
GPY24_RS120451289293..1289772-480WP_065818787.1GNAT family N-acetyltransferase-
GPY24_RS120501289917..1290873-957WP_197467496.1hypothetical protein-
GPY24_RS120551290930..1291463-534WP_065818788.1GNAT family N-acetyltransferase-
GPY24_RS120601291614..1292009-396WP_000870857.1DUF3465 domain-containing protein-
GPY24_RS120651292165..1293040-876WP_065818789.1hypothetical protein-
GPY24_RS120701293070..1293159-90WP_084834173.1DUF3265 domain-containing protein-
GPY24_RS120751293176..1293574-399WP_156478402.1hypothetical protein-
GPY24_RS120801293602..1293727-126Protein_1209DUF3265 domain-containing protein-
GPY24_RS120851294183..1294428-246WP_000643599.1hypothetical proteinAntitoxin
GPY24_RS120901294415..1294681-267WP_000589153.1BrnT family toxinToxin
GPY24_RS120951294858..1295322-465WP_158118642.1hypothetical protein-
GPY24_RS121001295440..1295733-294WP_158118643.1hypothetical protein-
GPY24_RS121051295721..1295813-93WP_156478403.1acetyltransferase-
GPY24_RS121101295870..1296145-276WP_065819779.1hypothetical protein-
GPY24_RS121151296185..1296334-150WP_080478972.1DUF3265 domain-containing protein-
GPY24_RS121201296292..1296576-285Protein_1217DUF2971 domain-containing protein-
GPY24_RS121251296696..1297397-702WP_197467433.1IS21-like element helper ATPase IstB-
GPY24_RS121301297408..1298940-1533WP_065818814.1IS21 family transposase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegron--1287888..131523127343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10062.32 Da        Isoelectric Point: 7.3171

>T144962 WP_000589153.1 NZ_CP046804:c1294681-1294415 [Vibrio cidicii]
MIKFEFDENKSRSNLEKHGIDFHTAQGLWNDSDLIEIPANTSDEPRYLVVGLLNGKHWSGVITYRGANIRIISVRRSRKA
EVSLYESA

Download         Length: 267 bp

>T144962 NZ_CP062247:c3694650-3694543 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9504.80 Da        Isoelectric Point: 6.2241

>AT144962 WP_000643599.1 NZ_CP046804:c1294428-1294183 [Vibrio cidicii]
MKAHEFDAKFESDDDDIVMDLDLSQAKRPMYKQKRVNVDFPAWMLESLDREASRIGVTRQSIIKIWLAERLESVSHHSSV
R

Download         Length: 246 bp

>AT144962 NZ_CP062247:3694699-3694765 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A151JG87

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A151JFU0

References