Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 811756..812284 Replicon chromosome
Accession NZ_CP046791
Organism Vibrio navarrensis strain 2462-79

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPY30_RS03615 Protein ID WP_158133144.1
Coordinates 811994..812284 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GPY30_RS03610 Protein ID WP_095456986.1
Coordinates 811756..812004 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPY30_RS03590 806897..807490 + 594 WP_158133140.1 NAD(P)H-dependent oxidoreductase -
GPY30_RS03595 807716..808195 - 480 WP_158133141.1 helix-turn-helix domain-containing protein -
GPY30_RS03600 808180..809550 - 1371 WP_158133142.1 type II toxin-antitoxin system HipA family toxin -
GPY30_RS03605 810192..811562 + 1371 WP_158133143.1 Fic family protein -
GPY30_RS03610 811756..812004 + 249 WP_095456986.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GPY30_RS03615 811994..812284 + 291 WP_158133144.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GPY30_RS03620 812346..812573 + 228 WP_158133145.1 AlpA family transcriptional regulator -
GPY30_RS03625 812606..813562 - 957 Protein_679 hypothetical protein -
GPY30_RS03630 813938..814594 + 657 WP_158134839.1 inovirus Gp2 family protein -
GPY30_RS03635 814632..814883 - 252 WP_158133146.1 hypothetical protein -
GPY30_RS03640 814998..815429 + 432 Protein_682 ribonuclease H -
GPY30_RS03645 815685..816128 - 444 WP_158133147.1 DUF2787 domain-containing protein -
GPY30_RS03650 816140..816595 - 456 WP_158133148.1 DUF2787 domain-containing protein -
GPY30_RS03655 816592..817068 - 477 WP_158133149.1 DNA repair protein RadC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 808180..820401 12221


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(12-75)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11115.99 Da        Isoelectric Point: 10.5696

>T144939 WP_158133144.1 NZ_CP046791:811994-812284 [Vibrio navarrensis]
MTYKLSFKKSALKEWQKLGATLQQQFKKKLAERLENPHVPASKLSGADNVYKIKLRQSGYRLVYKVEDDVVIVTVLAVGK
RERSDVYRKAMTRLDD

Download         Length: 291 bp

>T144939 NZ_CP062246:c4569657-4569316 [Escherichia coli]
ATGACTGACACGCATTCTATTGCACAACCGTTCGAAGCAGAAGTCTCCCCGGCAAATAACCGTCATGTCACCGTCGGTTA
TGCGAGTCGCTACCCGGATTACAGCCGTATTCCCGCCATCACCCTGAAAGGTCAGTGGCTGGAAGCCGCCGGTTTTGCCA
CTGGCACGGCGGTAGATGTCAAAGTGATGGAAGGCTGTATTGTCCTCACCGCCCAACCACCCGCCGCCGAGGAGAGCGAA
CTGATGCAGTCGCTACGCCAGGTGTGCAAACTGTCGGCGCGTAAACAAAAGCAGGTGCAGGCGTTTATTGGAGTGATTGC
CGGTAAACAGAAAGTCGCGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9074.33 Da        Isoelectric Point: 3.9610

>AT144939 WP_095456986.1 NZ_CP046791:811756-812004 [Vibrio navarrensis]
MTTRILADVAASITELKANPMKVANSAYGEPVAVLNRNEPAFYCVPAEAYELMMDRLEDLELLAIAKERESEESISVNID
DL

Download         Length: 249 bp

>AT144939 NZ_CP062246:4569652-4569728 [Escherichia coli]
AGTCATAACTGCTATTCTCCAGGAATAGTGATTGTGATTAGCGATGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References