Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 1140135..1140694 | Replicon | chromosome |
| Accession | NZ_CP046761 | ||
| Organism | Vibrio parahaemolyticus strain AM46865 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | GPY27_RS05775 | Protein ID | WP_140094869.1 |
| Coordinates | 1140135..1140413 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | GPY27_RS05780 | Protein ID | WP_005398409.1 |
| Coordinates | 1140410..1140694 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GPY27_RS05720 | 1135469..1135690 | + | 222 | WP_000076907.1 | VF530 family protein | - |
| GPY27_RS05725 | 1135697..1135822 | + | 126 | WP_140094867.1 | DUF3265 domain-containing protein | - |
| GPY27_RS05730 | 1135845..1136381 | + | 537 | WP_079883204.1 | hypothetical protein | - |
| GPY27_RS05735 | 1136587..1137138 | + | 552 | WP_031382156.1 | hypothetical protein | - |
| GPY27_RS05740 | 1137148..1137309 | + | 162 | WP_158113869.1 | hypothetical protein | - |
| GPY27_RS05745 | 1137500..1138024 | + | 525 | WP_175423329.1 | GNAT family N-acetyltransferase | - |
| GPY27_RS05750 | 1138008..1138202 | + | 195 | WP_079883203.1 | DUF3265 domain-containing protein | - |
| GPY27_RS05755 | 1138278..1138580 | + | 303 | WP_069486071.1 | hypothetical protein | - |
| GPY27_RS05760 | 1138605..1138697 | + | 93 | WP_079883202.1 | DUF3265 domain-containing protein | - |
| GPY27_RS05765 | 1138737..1139588 | + | 852 | WP_069486070.1 | hypothetical protein | - |
| GPY27_RS05770 | 1139585..1140028 | + | 444 | WP_086495621.1 | hypothetical protein | - |
| GPY27_RS05775 | 1140135..1140413 | - | 279 | WP_140094869.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| GPY27_RS05780 | 1140410..1140694 | - | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| GPY27_RS05785 | 1140918..1141328 | + | 411 | WP_079880021.1 | GFA family protein | - |
| GPY27_RS05790 | 1141368..1141445 | + | 78 | WP_140095673.1 | DUF3265 domain-containing protein | - |
| GPY27_RS05795 | 1142583..1143497 | + | 915 | WP_140095600.1 | hypothetical protein | - |
| GPY27_RS05800 | 1143610..1144565 | + | 956 | Protein_1034 | hypothetical protein | - |
| GPY27_RS05805 | 1144589..1144681 | + | 93 | WP_199251719.1 | DUF3265 domain-containing protein | - |
| GPY27_RS05810 | 1144728..1145447 | + | 720 | WP_140095611.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1101190..1166315 | 65125 | |
| - | inside | Integron | - | - | 1102315..1164695 | 62380 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10890.63 Da Isoelectric Point: 4.5482
>T144914 WP_140094869.1 NZ_CP046761:c1140413-1140135 [Vibrio parahaemolyticus]
MILWEEESLNDREKIFKFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFKFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T144914 NZ_CP062246:248788-249186 [Escherichia coli]
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
ATGCGGGTATTCAAAACAAAACTTATTCGCCTGCAACTTACAGCAGAGGAACTTGATGCGTTAACGGCGGATTTTATTTC
CTATAAGCGTGACGGTGTTTTGCCAGATATATTTGGTCGCGATGCACTCTACGACGACTCCTTTACCTGGCCATTAATCA
AATTTGAGCGAGTTGCTCATATTCATCTGGCAAATGAGAATAATCCATTTCCGCCACAGTTGCGCCAATTCAGCAGAACG
AATGACGAAGCGCATTTGGTATATTGTCAGGGGGCGTTTGATGAGCAAGCATGGTTGCTCATTGCCATTCTGAAACCTGA
ACCTCATAAACTGGCTCGAGATAACAACCAAATGCATAAAATTGGGAAAATGGCAGAAGCGTTTCGCATGCGTTTTTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT144914 WP_005398409.1 NZ_CP046761:c1140694-1140410 [Vibrio parahaemolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT144914 NZ_CP062246:248492-248785 [Escherichia coli]
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
ATGCATCGAATTCTCGCTGAAAAATCGGTCAATATCACTGAGTTACGTAAAAACCCAGCTAAATACTTTATTGATCAACC
GGTTGCGGTTCTTTCTAATAATCGCCCCGCAGGATATCTCTTAAGTGCCAGCGCATTCGAAGCGTTAATGGACATGCTTG
CTGAACAAGAGGAGAAAAAGCCCATAAAGGCGCGCTTCCGTCCAAGTGCTGCAAGATTAGAGGAAATTACACGCCGCGCT
GAACAATATCTTAATGATATGACGGATGATGATTTCAATGACTTTAAGGAATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|