Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1957921..1958192 Replicon chromosome
Accession NZ_CP046716
Organism Escherichia coli strain T16R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1958051..1958154 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1957921..1958192 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPL39_RS09325 1954476..1955138 - 663 WP_000944256.1 exodeoxyribonuclease X -
GPL39_RS09330 1955162..1955818 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
GPL39_RS09335 1955920..1956150 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GPL39_RS09340 1956289..1956663 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GPL39_RS09345 1956667..1957539 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
GPL39_RS09350 1957552..1957893 + 342 WP_000976472.1 YebY family protein -
- 1957921..1958192 - 272 - - Antitoxin
- 1958051..1958154 + 104 - - Toxin
GPL39_RS09355 1958289..1958945 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GPL39_RS09360 1958946..1959137 - 192 WP_001296140.1 YebW family protein -
GPL39_RS09365 1959242..1959478 - 237 WP_001295499.1 DUF1480 family protein -
GPL39_RS09370 1959596..1961035 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T144728 NZ_CP046716:1958051-1958154 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT144728 NZ_CP046716:c1958192-1957921 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ATGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References