Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 655071..655590 Replicon chromosome
Accession NZ_CP046673
Organism Citrobacter sp. 172116965

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPJ68_RS03180 Protein ID WP_016155559.1
Coordinates 655071..655352 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0V9JX71
Locus tag GPJ68_RS03185 Protein ID WP_016155558.1
Coordinates 655342..655590 (-) Length 83 a.a.

Genomic Context

GPJ68_RS03165GPJ68_RS03205GPJ68_RS03170GPJ68_RS03175GPJ68_RS03180GPJ68_RS03185GPJ68_RS03190GPJ68_RS03195GPJ68_RS03200GPJ68_RS03210
Location: 652073..652537 (465 bp)
Type: Others
Protein ID: WP_016151476.1
Location: 658533..659741 (1209 bp)
Type: Others
Protein ID: WP_001339175.1
Location: 652559..653080 (522 bp)
Type: Others
Protein ID: WP_104651644.1
Location: 653080..655044 (1965 bp)
Type: Others
Protein ID: WP_104651645.1
Location: 655071..655352 (282 bp)
Type: Toxin
Protein ID: WP_016155559.1
Location: 655342..655590 (249 bp)
Type: Antitoxin
Protein ID: WP_016155558.1
Location: 655663..655842 (180 bp)
Type: Others
Protein ID: WP_049043256.1
Location: 655968..656480 (513 bp)
Type: Others
Protein ID: WP_180837117.1
Location: 656509..658425 (1917 bp)
Type: Others
Protein ID: Protein_626
Location: 659757..659876 (120 bp)
Type: Others
Protein ID: Protein_628
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GPJ68_RS03165652073..652537+465WP_016151476.1anaerobic ribonucleoside-triphosphate reductase-activating protein-
GPJ68_RS03170652559..653080-522WP_104651644.1hypothetical protein-
GPJ68_RS03175653080..655044-1965WP_104651645.1type VI secretion system tip protein VgrG-
GPJ68_RS03180655071..655352-282WP_016155559.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GPJ68_RS03185655342..655590-249WP_016155558.1hypothetical proteinAntitoxin
GPJ68_RS03190655663..655842-180WP_049043256.1hypothetical protein-
GPJ68_RS03195655968..656480-513WP_180837117.1hypothetical protein-
GPJ68_RS03200656509..658425-1917Protein_626type VI secretion system ATPase TssH-
GPJ68_RS03205658533..659741+1209WP_001339175.1IS4-like element ISVsa5 family transposase-
GPJ68_RS03210659757..659876-120Protein_628LysR family transcriptional regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11004.76 Da        Isoelectric Point: 10.4466

>T144699 WP_016155559.1 NZ_CP046673:c655352-655071 [Citrobacter sp. 172116965]
MTYNLEFLDVALKEWRKLSPTLREQFKKKLAERLENPHVPAARLSGKLHRYKIKLRSAGYRLVYQVEDEQVVVLVIAVGR
RDGDEVYHQANRR

Download         Length: 282 bp

>T144699 NZ_CP062228:2217424-2217798 [Escherichia coli]
ATGAAAACATTACCTGTATTACCCGGGCAGGCGGCCAGTTCTCGCCCGTCTCCTGTTGAAATCTGGCAGATACTGCTGTC
CCGACTGCTGGACCAGCACTACGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGCATCGATATCCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8987.28 Da        Isoelectric Point: 4.7513

>AT144699 WP_016155558.1 NZ_CP046673:c655590-655342 [Citrobacter sp. 172116965]
MPFHILTKTAASITDLKRNPMGTVNAGEGEAVAILNRNEPAFYCVPPAVYAYLLELAEDAELNRIADEREGGKRIKVSLN
DL

Download         Length: 249 bp

>AT144699 NZ_CP062228:2216967-2217335 [Escherichia coli]
GTGTCAGACACACTCCCCGGGACAACACTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTACCCTGCACCGTGAC
GCCCTGTTTCGGCGCCCGTCTGGTGCAGGAGGGTAACCGGTTGCATTACCTTGCCGACCGTGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGTTGCTGATGAAACAACTGGAGCTCATGCTCACCAGTGGT
GAACTCAGCCCCCGCTATCAGCATACCGTCACGCTGTATGCGAAAGGACTGACCTGCGAAGCCGATACCCTGGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAATGAAAAATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0V9JX71

References