Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1975392..1975537 Replicon chromosome
Accession NZ_CP046645
Organism Klebsiella pneumoniae strain EGKP3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1975428..1975530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1975392..1975537 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPU01_RS09530 (GPU01_09435) 1970522..1972582 + 2061 WP_004148850.1 oligopeptidase B -
GPU01_RS09535 (GPU01_09440) 1972586..1973245 - 660 WP_002911407.1 exodeoxyribonuclease X -
GPU01_RS09540 (GPU01_09445) 1973324..1973554 - 231 WP_002911406.1 DNA polymerase III subunit theta -
GPU01_RS09545 (GPU01_09450) 1973667..1974041 + 375 WP_004151448.1 CopC domain-containing protein YobA -
GPU01_RS09550 (GPU01_09455) 1974045..1974914 + 870 WP_004891049.1 copper homeostasis membrane protein CopD -
GPU01_RS09555 (GPU01_09460) 1974931..1975269 + 339 WP_002911404.1 YebY family protein -
- 1975392..1975537 - 146 - - Antitoxin
- 1975428..1975530 + 103 - - Toxin
GPU01_RS09560 (GPU01_09465) 1975905..1976048 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
GPU01_RS09565 (GPU01_09470) 1976153..1977121 - 969 WP_014907334.1 VirK/YbjX family protein -
GPU01_RS09570 (GPU01_09475) 1977278..1977931 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
GPU01_RS09575 (GPU01_09480) 1977928..1978119 - 192 WP_002911395.1 YebW family protein -
GPU01_RS09580 (GPU01_09485) 1978217..1978456 - 240 WP_002911393.1 YebV family protein -
GPU01_RS09585 (GPU01_09490) 1978572..1980005 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T144639 NZ_CP046645:1975428-1975530 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT144639 NZ_CP046645:c1975537-1975392 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References