144629

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 4852343..4852938 Replicon chromosome
Accession NZ_CP046621
Organism Pseudomonas alkylphenolica strain Neo

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPJ81_RS21965 Protein ID WP_157194091.1
Coordinates 4852645..4852938 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag GPJ81_RS21960 Protein ID WP_157194089.1
Coordinates 4852343..4852642 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GPJ81_RS21940 4848277..4849380 - 1104 WP_157194082.1 extracellular solute-binding protein -
GPJ81_RS21945 4849382..4850290 - 909 WP_157194083.1 N-carbamoylputrescine amidase -
GPJ81_RS21950 4850295..4851347 - 1053 WP_157194085.1 agmatine deiminase family protein -
GPJ81_RS21955 4851480..4852346 + 867 WP_157194087.1 LysR family transcriptional regulator -
GPJ81_RS21960 4852343..4852642 - 300 WP_157194089.1 putative addiction module antidote protein Antitoxin
GPJ81_RS21965 4852645..4852938 - 294 WP_157194091.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GPJ81_RS21970 4853369..4853590 + 222 WP_157194093.1 hypothetical protein -
GPJ81_RS21975 4853713..4853937 + 225 WP_157194095.1 DUF3077 domain-containing protein -
GPJ81_RS21980 4853944..4855155 - 1212 WP_157194097.1 YeeE/YedE family protein -
GPJ81_RS21985 4855257..4855733 + 477 WP_157194099.1 GNAT family N-acetyltransferase -
GPJ81_RS21990 4855834..4856343 + 510 WP_157194101.1 sigma-70 family RNA polymerase sigma factor -
GPJ81_RS21995 4856349..4857341 + 993 WP_198325380.1 FecR family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(7-96)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10635.41 Da        Isoelectric Point: 10.8628

>T144629 WP_157194091.1 NZ_CP046621:c4852938-4852645 [Pseudomonas alkylphenolica]
VLYRVLQTPGFSSWLVSIRDLRAKVAIARRIERASVGNLGDVKFVGGQVSEMRIDVGAGYRVYFTVRDGVVIVLLAGGDK
SSQSKDIQLARKLVKDV

Download         Length: 294 bp

>T144629 NZ_CP062204:2443255-2444577 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10553.11 Da        Isoelectric Point: 5.5656

>AT144629 WP_157194089.1 NZ_CP046621:c4852642-4852343 [Pseudomonas alkylphenolica]
MSLTLSTFDMATLLDSDEAISEYLSQVLADGDHEELIRALGYVAKARGMAQVATASGLGRESLYKALSPGAKPRFDTVLK
VIRALGIDLLALPHAPSNH

Download         Length: 300 bp

>AT144629 NZ_CP062204:2442989-2443255 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References