Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 4852343..4852938 Replicon chromosome
Accession NZ_CP046621
Organism Pseudomonas alkylphenolica strain Neo

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GPJ81_RS21965 Protein ID WP_157194091.1
Coordinates 4852645..4852938 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag GPJ81_RS21960 Protein ID WP_157194089.1
Coordinates 4852343..4852642 (-) Length 100 a.a.

Genomic Context

GPJ81_RS21955GPJ81_RS21970GPJ81_RS21975GPJ81_RS21985GPJ81_RS21990GPJ81_RS21995GPJ81_RS21940GPJ81_RS21945GPJ81_RS21950GPJ81_RS21960GPJ81_RS21965GPJ81_RS21980
Location: 4851480..4852346 (867 bp)
Type: Others
Protein ID: WP_157194087.1
Location: 4853369..4853590 (222 bp)
Type: Others
Protein ID: WP_157194093.1
Location: 4853713..4853937 (225 bp)
Type: Others
Protein ID: WP_157194095.1
Location: 4855257..4855733 (477 bp)
Type: Others
Protein ID: WP_157194099.1
Location: 4855834..4856343 (510 bp)
Type: Others
Protein ID: WP_157194101.1
Location: 4856349..4857341 (993 bp)
Type: Others
Protein ID: WP_198325380.1
Location: 4848277..4849380 (1104 bp)
Type: Others
Protein ID: WP_157194082.1
Location: 4849382..4850290 (909 bp)
Type: Others
Protein ID: WP_157194083.1
Location: 4850295..4851347 (1053 bp)
Type: Others
Protein ID: WP_157194085.1
Location: 4852343..4852642 (300 bp)
Type: Antitoxin
Protein ID: WP_157194089.1
Location: 4852645..4852938 (294 bp)
Type: Toxin
Protein ID: WP_157194091.1
Location: 4853944..4855155 (1212 bp)
Type: Others
Protein ID: WP_157194097.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GPJ81_RS219404848277..4849380-1104WP_157194082.1extracellular solute-binding protein-
GPJ81_RS219454849382..4850290-909WP_157194083.1N-carbamoylputrescine amidase-
GPJ81_RS219504850295..4851347-1053WP_157194085.1agmatine deiminase family protein-
GPJ81_RS219554851480..4852346+867WP_157194087.1LysR family transcriptional regulator-
GPJ81_RS219604852343..4852642-300WP_157194089.1putative addiction module antidote proteinAntitoxin
GPJ81_RS219654852645..4852938-294WP_157194091.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GPJ81_RS219704853369..4853590+222WP_157194093.1hypothetical protein-
GPJ81_RS219754853713..4853937+225WP_157194095.1DUF3077 domain-containing protein-
GPJ81_RS219804853944..4855155-1212WP_157194097.1YeeE/YedE family protein-
GPJ81_RS219854855257..4855733+477WP_157194099.1GNAT family N-acetyltransferase-
GPJ81_RS219904855834..4856343+510WP_157194101.1sigma-70 family RNA polymerase sigma factor-
GPJ81_RS219954856349..4857341+993WP_198325380.1FecR family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(7-96)

Antitoxin

Uncharacterized protein HI1420

(5-90)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10635.41 Da        Isoelectric Point: 10.8628

>T144629 WP_157194091.1 NZ_CP046621:c4852938-4852645 [Pseudomonas alkylphenolica]
VLYRVLQTPGFSSWLVSIRDLRAKVAIARRIERASVGNLGDVKFVGGQVSEMRIDVGAGYRVYFTVRDGVVIVLLAGGDK
SSQSKDIQLARKLVKDV

Download         Length: 294 bp

>T144629 NZ_CP062204:2443255-2444577 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAACGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CAGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGACCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAAAAGCTTACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTTAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTTCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAATTCCAGGTCTTCCAGTGGTTGATTGGCGCAACGGACGGTCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTCCTTGGCGGTACGGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTTTGGCGACAGCAAAGGTGCTGAGATTCCCGGAAGTGCAGATGCATGAAATCCTAAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCATGGACGGTTAAGCCGAGAATACGGTAGTAAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10553.11 Da        Isoelectric Point: 5.5656

>AT144629 WP_157194089.1 NZ_CP046621:c4852642-4852343 [Pseudomonas alkylphenolica]
MSLTLSTFDMATLLDSDEAISEYLSQVLADGDHEELIRALGYVAKARGMAQVATASGLGRESLYKALSPGAKPRFDTVLK
VIRALGIDLLALPHAPSNH

Download         Length: 300 bp

>AT144629 NZ_CP062204:2442989-2443255 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGCATTAAGCAGGCGACAATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TCACGACATTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACACTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References