Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2055816..2055961 | Replicon | chromosome |
| Accession | NZ_CP046612 | ||
| Organism | Klebsiella pneumoniae strain WCGKP294 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2055852..2055954 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2055816..2055961 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GPJ73_RS10075 | 2050946..2053006 | + | 2061 | WP_004148850.1 | oligopeptidase B | - |
| GPJ73_RS10080 | 2053010..2053669 | - | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| GPJ73_RS10085 | 2053748..2053978 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| GPJ73_RS10090 | 2054091..2054465 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| GPJ73_RS10095 | 2054469..2055338 | + | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| GPJ73_RS10100 | 2055355..2055693 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2055816..2055961 | - | 146 | - | - | Antitoxin |
| - | 2055852..2055954 | + | 103 | - | - | Toxin |
| GPJ73_RS10105 | 2056329..2056472 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| GPJ73_RS10110 | 2056577..2057545 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| GPJ73_RS10115 | 2057702..2058355 | + | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| GPJ73_RS10120 | 2058352..2058543 | - | 192 | WP_002911395.1 | YebW family protein | - |
| GPJ73_RS10125 | 2058641..2058880 | - | 240 | WP_002911393.1 | YebV family protein | - |
| GPJ73_RS10130 | 2058996..2060429 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T144587 NZ_CP046612:2055852-2055954 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT144587 NZ_CP046612:c2055961-2055816 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
