Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1859884..1860414 Replicon chromosome
Accession NZ_CP046609
Organism Burkholderia contaminans strain XL73

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag GON15_RS29555 Protein ID WP_076841743.1
Coordinates 1860151..1860414 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag GON15_RS29550 Protein ID WP_076841742.1
Coordinates 1859884..1860129 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GON15_RS29520 1854949..1855965 + 1017 WP_039358635.1 acetyltransferase -
GON15_RS29525 1856215..1856481 + 267 WP_046196769.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
GON15_RS29530 1856478..1856894 + 417 Protein_1639 type II toxin-antitoxin system VapC family toxin -
GON15_RS29535 1856943..1857182 - 240 Protein_1640 nucleotidyltransferase -
GON15_RS29540 1857196..1858263 - 1068 WP_039358630.1 hypothetical protein -
GON15_RS29545 1858604..1859767 + 1164 WP_039358627.1 amidohydrolase -
GON15_RS29550 1859884..1860129 + 246 WP_076841742.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
GON15_RS29555 1860151..1860414 + 264 WP_076841743.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GON15_RS29560 1860485..1861789 - 1305 WP_039358619.1 cobyrinate a,c-diamide synthase -
GON15_RS29565 1861792..1862394 - 603 WP_039358616.1 cob(I)yrinic acid a,c-diamide adenosyltransferase -
GON15_RS29570 1862432..1862809 - 378 WP_039358613.1 cobalamin biosynthesis protein -
GON15_RS29575 1862806..1863555 - 750 WP_039358610.1 uroporphyrinogen-III C-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-82)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10242.66 Da        Isoelectric Point: 6.0735

>T144579 WP_076841743.1 NZ_CP046609:1860151-1860414 [Burkholderia contaminans]
MAELDLEDIWRDTVGRGSLKQTDLYHRDLIGTMEALARGEKVGRTCIVRDGYFRYAVGSHVVFYRETEYTIDLIRVLHQR
MDIEQHL

Download         Length: 264 bp

>T144579 NZ_CP062160:c4828915-4828508 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATAGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9021.01 Da        Isoelectric Point: 5.6864

>AT144579 WP_076841742.1 NZ_CP046609:1859884-1860129 [Burkholderia contaminans]
MSQNASVSRRDHFAELVDTQVQSEQYGSASDVERTGLRLLESRDMQVRALQEALKAGEVSGALRPFDREAFLARMRAAHD
G

Download         Length: 246 bp

>AT144579 NZ_CP062160:c4829162-4828896 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTATGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References