Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 868404..869058 Replicon chromosome
Accession NZ_CP046582
Organism Erwinia sp. E602

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GKQ23_RS05380 Protein ID WP_212409961.1
Coordinates 868651..869058 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GKQ23_RS05375 Protein ID WP_056231907.1
Coordinates 868404..868670 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ23_RS05360 (GKQ23_05345) 866534..867184 + 651 WP_212411566.1 hemolysin III family protein -
GKQ23_RS05365 (GKQ23_05350) 867191..868177 - 987 WP_212409959.1 tRNA-modifying protein YgfZ -
GKQ23_RS05370 (GKQ23_05355) 868212..868388 + 177 WP_212409960.1 hypothetical protein -
GKQ23_RS05375 (GKQ23_05360) 868404..868670 + 267 WP_056231907.1 FAD assembly factor SdhE Antitoxin
GKQ23_RS05380 (GKQ23_05365) 868651..869058 + 408 WP_212409961.1 protein YgfX Toxin
GKQ23_RS05385 (GKQ23_05370) 869058..869750 + 693 WP_056231911.1 two-component system response regulator CreB -
GKQ23_RS05390 (GKQ23_05375) 869750..871174 + 1425 WP_212409962.1 two-component system sensor histidine kinase CreC -
GKQ23_RS05395 (GKQ23_05380) 871255..872607 + 1353 WP_212409963.1 cell envelope integrity protein CreD -
GKQ23_RS05400 (GKQ23_05385) 872679..873197 - 519 WP_056232341.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 16075.09 Da        Isoelectric Point: 12.5019

>T144527 WP_212409961.1 NZ_CP046582:868651-869058 [Erwinia sp. E602]
VARWQSELRLSRCACRLSLLLHGAVLMSLLLAHWPASVTPWWGVLLALTLLESVRSQRRIRRRTGYLSWSLGRQLRWREQ
RWHLQRPPWLTPWAILLTLRNARGKRERLWLFADAMPPAAWRLLRQRLLMPEGDV

Download         Length: 408 bp

>T144527 NZ_CP062122:4373586-4373837 [Pseudomonas sp. ADPe]
ATGTCCAGGAACGAGAAACTGCTGGCCAAGCTACTCAACGAAAGCACCAGCTTTACCTGGCAGGAGCTTGTGACACTGCT
GCGTTGGCTGGGCTACAGGCAATTGGAGGGCAGCGGGAGCCGGGTCAAGTTCGACAACGGCGACCCGCAGGCGTTGATCA
ACCTTCACAAGCCGCACCCGGGCAACGAGCTGAAAGCCTATGTCCGGCGCCAGATCATCGAGCACCTCAAGGCGGGGGAA
CTGATTCCGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10381.95 Da        Isoelectric Point: 6.2133

>AT144527 WP_056231907.1 NZ_CP046582:868404-868670 [Erwinia sp. E602]
MDISNKSRIHWACRRGMRELDMAIMPFFQHEFDSLTDADKQVFVQLLKSDDPDLFNWLMNHGEPADPELKRMVLLIQQRN
QQRGPVAI

Download         Length: 267 bp

>AT144527 NZ_CP062122:4373834-4374175 [Pseudomonas sp. ADPe]
GTGAACAACCTGCTGCAATACCGGGGCTATTACGGCTCCATCGAAGCCAGCACCGAGGACAACTGCCTGTTCGGCAAGCT
GCTCTTCATCCGCGCGCTGGTCAACTACGAAGGCGAGACGGTGGCCGAACTGCAGGCCGCTTTCCGCGAGGCGGTGGACG
ACTACCTGGCCACATGCCAGGCGCAGGGGCAGGAGCCGGAAGTGCCTTGCAAGGGATCGTTCAACGTGCGGGTCGGCCAT
GACTTGCATCTGGCAGCGAGCCTGGCAGCCAACCGGCAGCACATGAGCCTGAACGACCTCACCCGGCAGGCGCTGAGCGA
GTATTTGCAGCACCACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References