Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 42692..43266 Replicon plasmid unnamed1
Accession NZ_CP046581
Organism Erwinia sp. E602

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GKQ23_RS00160 Protein ID WP_056237207.1
Coordinates 42692..43015 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GKQ23_RS00165 Protein ID WP_056237204.1
Coordinates 43015..43266 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ23_RS00145 (GKQ23_00145) 39097..40206 + 1110 WP_212408275.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -
GKQ23_RS00150 (GKQ23_00150) 40237..41532 + 1296 WP_212408276.1 maltoporin -
GKQ23_RS00155 (GKQ23_00155) 41617..42513 + 897 WP_212408277.1 maltose operon protein MalM -
GKQ23_RS00160 (GKQ23_00160) 42692..43015 - 324 WP_056237207.1 hypothetical protein Toxin
GKQ23_RS00165 (GKQ23_00165) 43015..43266 - 252 WP_056237204.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GKQ23_RS00170 (GKQ23_00175) 43700..44461 - 762 WP_101505016.1 DNA-binding transcriptional regulator YciT -
GKQ23_RS00175 (GKQ23_00180) 44565..45824 - 1260 WP_212408278.1 DUF1479 domain-containing protein -
GKQ23_RS00180 (GKQ23_00185) 46136..46381 + 246 WP_212408279.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
GKQ23_RS00185 (GKQ23_00190) 46362..46637 + 276 WP_212408280.1 Txe/YoeB family addiction module toxin -
GKQ23_RS00190 (GKQ23_00195) 46864..47097 + 234 WP_056238460.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB 1..325969 325969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12253.14 Da        Isoelectric Point: 10.5053

>T144520 WP_056237207.1 NZ_CP046581:c43015-42692 [Erwinia sp. E602]
MSDTFKATLKFKALAKKEWDSLNPSIREKFAKVLKKRAASYEALTMPANRLSLQHNCYKIKLRNDGFRLAYTVTSDDAGN
VRVTVTVVAVDRRDEIYEDLNRRLAGK

Download         Length: 324 bp

>T144520 NZ_CP062122:c1846239-1845943 [Pseudomonas sp. ADPe]
ATGGAGAAATCGGCACCCCATTGCCGTCTCGATCGAGTCAAGTCGCTGCTTGCCCAGGGCAGGGTTCGCGCGACCTATTC
CGCGCTCTCCGGCGGCGCGGCGCTGGGGTTGGACTTCGCCGGCATGCTGGCGGTCATCGAGGCCCTGGCGCCCCGCGATT
TCCACAAGAGCATGACGACTCACGCCGATCATCGGGTCTGGCAGGACGTCTACCGACCTTCGACCGCCGTGGGGCGGATC
TATCTGAAGTTGACCGTCATAGACGATGTGCTTGTCGTGTCCTTCAAGGAGCTATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9289.55 Da        Isoelectric Point: 4.4192

>AT144520 WP_056237204.1 NZ_CP046581:c43266-43015 [Erwinia sp. E602]
MITENILSRKTASITEFKKNPTAAMNESHGEPVAVLNHNKPAFYCVPPAMFELMFEHVSDALLLQKALDRAGDDELDVSW
DDL

Download         Length: 252 bp

>AT144520 NZ_CP062122:c1845940-1845539 [Pseudomonas sp. ADPe]
ATGAAATGTCCCCTCTGCGGTGGAGCCGAACTGCTCCACGAGACCCGCGACCTTCCCTATGCCTACAAGGGGGAGAGCAC
CCTGATAACGGCTGTGCGCGGTGAGTTCTGCCCGGCCTGTGGCGAGGCGGTGCTGGACGCCGAAGAGTCGGCGCGGGTGA
ATGCCCAGATGCTGGCCTTCAACAAGCGGGTGAACGCTTCGATGGTCGATCCGGGATTCATCGCCGCGGTACGCAAGAAG
CTGGCGCTGGACCAGCGCGAGGCCGCGGAGATCTTCGGTGGCGGCGTGAACGCGTTCTCCCGCTACGAGAATGGCAAGAC
GCGCCCGCCGTTGGCGCTGGTCAAGCTGCTCAAGGTGCTCGACCGCCATCCCGAATTGCTGGAAGAGGTGCGCGCGGGGT
AA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References