Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 3602..4245 Replicon plasmid unnamed1
Accession NZ_CP046581
Organism Erwinia sp. E602

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag GKQ23_RS00020 Protein ID WP_056237281.1
Coordinates 3829..4245 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag GKQ23_RS00015 Protein ID WP_056237284.1
Coordinates 3602..3832 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ23_RS00005 (GKQ23_00005) 1..411 + 411 WP_249168391.1 cupin domain-containing protein -
GKQ23_RS00010 (GKQ23_00010) 1499..3073 - 1575 WP_249168392.1 methyl-accepting chemotaxis protein -
GKQ23_RS00015 (GKQ23_00015) 3602..3832 + 231 WP_056237284.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GKQ23_RS00020 (GKQ23_00020) 3829..4245 + 417 WP_056237281.1 type II toxin-antitoxin system VapC family toxin Toxin
GKQ23_RS00025 (GKQ23_00025) 4297..5709 - 1413 WP_212408257.1 FAD-binding oxidoreductase -
GKQ23_RS00030 (GKQ23_00030) 6609..8207 - 1599 WP_212408258.1 gamma-glutamyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB 1..325969 325969


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-129)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15111.48 Da        Isoelectric Point: 8.5428

>T144519 WP_056237281.1 NZ_CP046581:3829-4245 [Erwinia sp. E602]
MTKTFMLDTNICSFIMREQPETVIRRLEQAVLRNHRIVVSAITYAEMRFGAIGKKASPRHAKLVEAFCSRLDAILPWDRA
AVDATTEVKTALFAAGTPIGPNDTGIAGHAISAGAVLVTNNVREFERVTGLALEDWAK

Download         Length: 417 bp

>T144519 NZ_CP062122:c1298651-1297881 [Pseudomonas sp. ADPe]
ATGGCCCTCGACGCCGGCGCCGAACTGTGGCGCGAATGCCGGGGCGAGCAGGCCATCGCCCCGCTGCGGGGCAAGCTGGT
GCGCCTGGTGGAGAGCCAGGAGCAGGTCGCGACCCTGCAACTGGTGGATACCCTGGAGGAGCAGGCCCTGCTGGAAGAGC
TGATCGAGACCAGCAAGCCGCACCTGCCGCCGTCCACCGAAACCCTGCACTACCTGCTCAAGACGCCGTTCCGCTACCCG
CCGCTGCGTTGGGGCTCGCGCTTCGGCCGCCGCCACGAACCCAGCCTGTTCTACGCCGCGTTGCGCCTGGAGACGGCCAT
GGCCGAGGCGGCCTATTACCGCTTCGTGCTCTGGGAGGGCATGGCCAGCCCGCCGCCCAGCGGGCGCATCCTTTCCGAGC
ACGCTTCCTTCGAGGCGCGTTTCCAGGTGCAACGGGGCATACGCCTGCAGGCGCCGCCCTTCGACAGCTATGCCGAGCGC
CTGCAGGACCCGCAGGACTACCGCCTGACCCAGGCGCTGGGCAGCGCGATGCGCGCTGCCGCGGTGGAGGCCTTCGAATA
CCGCTCGGCGCGCTGCCCGGAAGGTGGGCTGAATGCCGCGCTCTTCGTGCCTTCGGCCTTTGTCGACAAGCGCCCGCGCA
ACCTCATGCCCTGGCTGTGCGAGACCACCGCCGACTACGTGGCCTTCAAGCATGCCCAGGTGCCGGGGGCGCCGCGGCTG
TTCCCGCGCGCGGGATTCCTGGTCGAGGGCGACCTGCCGCACCCGGCGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8800.84 Da        Isoelectric Point: 4.3730

>AT144519 WP_056237284.1 NZ_CP046581:3602-3832 [Erwinia sp. E602]
MRTVSVFKNGNNRAIRLPRDLDFDGVSELEILRDGDTLILRPVRPTWGSYLQEEKADKDFMADRDDVVSDEGRFEL

Download         Length: 231 bp

>AT144519 NZ_CP062122:c1299020-1298652 [Pseudomonas sp. ADPe]
ATGAGCGCACTGATCCGGGAAACTCCGTCGGCCGATCTGGTCCTGGCCAAGGCGGTACTGGCTGCCCGTGAGCAACTGGG
CATGACGCAGCAGGAGCTGGCCGCCATCGTCGGCGTCGATCGCAGCGCGGTGAGCCGCTGGAAGAGCGGCGGCCTGCGGG
TGGGCAGCAAGACCGGCGAGCTGGCGCTGCTGCTGGTGCGGGTATACCGCGCGCTCTTCGCCCTGTTCGGCGGCAACCTG
GAGGACATGCGCCACTTCCTGCGCACCCCCAACCGCCACCTGAGCGGTGTGCCGCTGCAGCGGATGGAGCAGGTGCAGGG
CCTGGTGCAGGTGGTCGAGTACCTCGACGCCATCCGGGGCAAGATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References