Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3943406..3944066 Replicon chromosome
Accession NZ_CP046557
Organism Leclercia sp. 1106151

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GNG29_RS18760 Protein ID WP_103176874.1
Coordinates 3943406..3943819 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GNG29_RS18765 Protein ID WP_103176875.1
Coordinates 3943800..3944066 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNG29_RS18740 3939409..3941142 - 1734 WP_103176870.1 single-stranded-DNA-specific exonuclease RecJ -
GNG29_RS18745 3941148..3941861 - 714 WP_156655193.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GNG29_RS18750 3941883..3942779 - 897 WP_103176872.1 site-specific tyrosine recombinase XerD -
GNG29_RS18755 3942880..3943401 + 522 WP_103176873.1 flavodoxin FldB -
GNG29_RS18760 3943406..3943819 - 414 WP_103176874.1 protein YgfX Toxin
GNG29_RS18765 3943800..3944066 - 267 WP_103176875.1 FAD assembly factor SdhE Antitoxin
GNG29_RS18770 3944370..3945350 + 981 WP_156655194.1 tRNA-modifying protein YgfZ -
GNG29_RS18775 3945436..3946095 - 660 WP_103176877.1 hemolysin III family protein -
GNG29_RS18780 3946261..3946572 - 312 WP_103176878.1 N(4)-acetylcytidine aminohydrolase -
GNG29_RS18785 3946625..3947356 + 732 WP_103176879.1 MurR/RpiR family transcriptional regulator -
GNG29_RS18790 3947471..3948904 + 1434 WP_156655195.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16236.07 Da        Isoelectric Point: 10.7511

>T144509 WP_103176874.1 NZ_CP046557:c3943819-3943406 [Leclercia sp. 1106151]
VVLWQSDLRVSWRAQWMSLLLHGLVAAVILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWQES
EWEIVGTPWMLNSGMMLRLRKGAGQRCHHLWLAADSMDEAEWRDLRRMMSHQPTQGR

Download         Length: 414 bp

>T144509 NZ_CP062074:490252-490602 [Bacillus velezensis]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
GCAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.97 Da        Isoelectric Point: 4.8382

>AT144509 WP_103176875.1 NZ_CP046557:c3944066-3943800 [Leclercia sp. 1106151]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKHLFVRLLENDDPDLFNWLMNHGKPADAELQRMVLLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT144509 NZ_CP062074:489965-490246 [Bacillus velezensis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCTGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References