Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 517665..517936 Replicon chromosome
Accession NZ_CP046539
Organism Escherichia coli strain FHI_NMBU_10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 517795..517898 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 517665..517936 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GOE21_RS02590 514220..514882 - 663 WP_000944256.1 exodeoxyribonuclease X -
GOE21_RS02595 514906..515562 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
GOE21_RS02600 515664..515894 - 231 WP_000916763.1 DNA polymerase III subunit theta -
GOE21_RS02605 516033..516407 + 375 WP_000204699.1 CopC domain-containing protein YobA -
GOE21_RS02610 516411..517283 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
GOE21_RS02615 517296..517637 + 342 WP_000976492.1 YebY family protein -
- 517665..517936 - 272 - - Antitoxin
- 517795..517898 + 104 - - Toxin
GOE21_RS02620 518033..518689 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
GOE21_RS02625 518690..518881 - 192 WP_001296140.1 YebW family protein -
GOE21_RS02630 518986..519222 - 237 WP_001295499.1 DUF1480 family protein -
GOE21_RS02635 519340..520779 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T144471 NZ_CP046539:517795-517898 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT144471 NZ_CP046539:c517936-517665 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References