Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 4211764..4212422 Replicon chromosome
Accession NZ_CP046535
Organism Sphingomonas sp. LMO-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GNT64_RS19950 Protein ID WP_156681095.1
Coordinates 4211764..4212150 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GNT64_RS19955 Protein ID WP_197277141.1
Coordinates 4212147..4212422 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNT64_RS19945 4207238..4211761 + 4524 WP_156681778.1 glutamate synthase large subunit -
GNT64_RS19950 4211764..4212150 - 387 WP_156681095.1 type II toxin-antitoxin system VapC family toxin Toxin
GNT64_RS19955 4212147..4212422 - 276 WP_197277141.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GNT64_RS19960 4212523..4213200 + 678 WP_156681097.1 glutathione S-transferase family protein -
GNT64_RS19965 4213240..4214142 - 903 WP_156681098.1 SDR family oxidoreductase -
GNT64_RS19975 4214684..4215496 - 813 WP_156681099.1 hypothetical protein -
GNT64_RS19980 4215619..4216029 + 411 WP_156681100.1 hypothetical protein -
GNT64_RS19985 4216363..4216995 - 633 WP_156681101.1 hypothetical protein -
GNT64_RS21690 4217227..4217364 + 138 WP_197277142.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Antitoxin VapB-like

(1-87)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13547.76 Da        Isoelectric Point: 6.4585

>T144467 WP_156681095.1 NZ_CP046535:c4212150-4211764 [Sphingomonas sp. LMO-1]
MTLVVDSSAIVAIILAEAEAAAFGERLLDNDAVMAAPNQLETLMVLSRRPGAEAALSGVLRAYNIQIAPFTADLVPLAHD
AFVRFGKGRHAAGLNFGDCIAYALARARRAPLLFKGRDFALTDVVPAL

Download         Length: 387 bp

>T144467 NZ_CP061970:893761-894171 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10269.52 Da        Isoelectric Point: 4.6085

>AT144467 WP_197277141.1 NZ_CP046535:c4212422-4212147 [Sphingomonas sp. LMO-1]
MALSIKDEELDRKVRRLAALRKTSFTGAIRLAVDNELAREAVDPEREARRVRAEAAVKAAQEWFRAGPVDWSMTDDEILG
YDENGVPTQPE

Download         Length: 276 bp

>AT144467 NZ_CP061970:893514-893780 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References