Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5038203..5038474 Replicon chromosome
Accession NZ_CP046527
Organism Escherichia coli strain RM19259

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5038241..5038344 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5038203..5038474 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN312_RS25290 5035360..5036799 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GN312_RS25295 5036917..5037153 + 237 WP_001295499.1 DUF1480 family protein -
GN312_RS25300 5037258..5037449 + 192 WP_001296140.1 YebW family protein -
GN312_RS25305 5037450..5038106 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 5038203..5038474 + 272 - - Antitoxin
- 5038241..5038344 - 104 - - Toxin
GN312_RS25310 5038502..5038843 - 342 WP_000976483.1 YebY family protein -
GN312_RS25315 5038856..5039728 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
GN312_RS25320 5039732..5040106 - 375 WP_000168751.1 CopC domain-containing protein YobA -
GN312_RS25325 5040245..5040475 + 231 WP_000916763.1 DNA polymerase III subunit theta -
GN312_RS25330 5040577..5041233 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
GN312_RS25335 5041257..5041919 + 663 WP_000944244.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T144393 NZ_CP046527:c5038344-5038241 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT144393 NZ_CP046527:5038203-5038474 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References