Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 845668..846328 Replicon chromosome
Accession NZ_CP046509
Organism Erwinia sp. J780

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GN242_RS03830 Protein ID WP_156286937.1
Coordinates 845915..846328 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GN242_RS03825 Protein ID WP_154753544.1
Coordinates 845668..845934 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GN242_RS03810 842929..843537 - 609 WP_156286936.1 HD domain-containing protein -
GN242_RS03815 843750..844403 + 654 WP_154753542.1 hemolysin III family protein -
GN242_RS03820 844455..845441 - 987 WP_154753543.1 tRNA-modifying protein YgfZ -
GN242_RS03825 845668..845934 + 267 WP_154753544.1 FAD assembly factor SdhE Antitoxin
GN242_RS03830 845915..846328 + 414 WP_156286937.1 hypothetical protein Toxin
GN242_RS03835 846321..847016 + 696 WP_156286938.1 two-component system response regulator CreB -
GN242_RS03840 847016..848434 + 1419 WP_156286939.1 two-component system sensor histidine kinase CreC -
GN242_RS03845 848524..849891 + 1368 WP_156286940.1 cell envelope integrity protein CreD -
GN242_RS03850 849962..850480 - 519 WP_156288178.1 flavodoxin FldB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16234.21 Da        Isoelectric Point: 11.5800

>T144351 WP_156286937.1 NZ_CP046509:845915-846328 [Erwinia sp. J780]
VARWQCNLRPSRQARTLSLLLHSAVMLALLLAPWPDSAALPRAILMLLVLIECLRGQQRLLRCRGDFILREGRVLIWQQR
QWRMTSRPWLSRLAMCLSLQETSGCRQRLWLFADGMENSEWRLLRQQLLNEKELRDE

Download         Length: 414 bp

>T144351 NZ_CP061914:1946194-1946445 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10400.86 Da        Isoelectric Point: 4.6413

>AT144351 WP_154753544.1 NZ_CP046509:845668-845934 [Erwinia sp. J780]
MDISNKSRIHWACRRGMRELDISIMPFFQYEFDSLTDEDKQLFVRLLESDDPDLFNWLMNHGEPADAELQRMVALIQERN
KARGPVAM

Download         Length: 267 bp

>AT144351 NZ_CP061914:1946442-1946696 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References