Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
| Location | 2488403..2488959 | Replicon | chromosome |
| Accession | NZ_CP046495 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO597 | ||
Toxin (Protein)
| Gene name | parE | Uniprot ID | - |
| Locus tag | IXO597_RS11760 | Protein ID | WP_229001948.1 |
| Coordinates | 2488708..2488959 (+) | Length | 84 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A854CIX2 |
| Locus tag | IXO597_RS11755 | Protein ID | WP_011408759.1 |
| Coordinates | 2488403..2488681 (+) | Length | 93 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO597_RS11735 (IXO597_011855) | 2484047..2485369 | + | 1323 | WP_069964865.1 | 3-phosphoshikimate 1-carboxyvinyltransferase | - |
| IXO597_RS11740 (IXO597_011860) | 2485393..2485683 | - | 291 | Protein_2238 | IS5/IS1182 family transposase | - |
| IXO597_RS11745 (IXO597_011865) | 2485773..2486957 | + | 1185 | WP_263115681.1 | IS256-like element IS1113 family transposase | - |
| IXO597_RS11750 (IXO597_011875) | 2487863..2488207 | + | 345 | WP_199285675.1 | hypothetical protein | - |
| IXO597_RS11755 (IXO597_011880) | 2488403..2488681 | + | 279 | WP_011408759.1 | CopG family ribbon-helix-helix protein | Antitoxin |
| IXO597_RS11760 (IXO597_011885) | 2488708..2488959 | + | 252 | WP_229001948.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| IXO597_RS11765 | 2489036..2489290 | + | 255 | WP_198912806.1 | hypothetical protein | - |
| IXO597_RS11770 (IXO597_011890) | 2489283..2489417 | + | 135 | WP_011051575.1 | hypothetical protein | - |
| IXO597_RS11775 (IXO597_011895) | 2489486..2489740 | + | 255 | WP_223293127.1 | hypothetical protein | - |
| IXO597_RS11780 (IXO597_011900) | 2489957..2490076 | + | 120 | Protein_2246 | IS3 family transposase | - |
| IXO597_RS11785 | 2490045..2490173 | + | 129 | WP_012444694.1 | hypothetical protein | - |
| IXO597_RS11795 (IXO597_011915) | 2490604..2491005 | - | 402 | WP_011259345.1 | H-NS family nucleoid-associated regulatory protein | - |
| IXO597_RS11800 (IXO597_011920) | 2491227..2491403 | + | 177 | Protein_2249 | DUF3606 domain-containing protein | - |
| IXO597_RS11805 (IXO597_011930) | 2491685..2492022 | + | 338 | Protein_2250 | ATP-dependent DNA ligase | - |
| IXO597_RS11810 (IXO597_011935) | 2492098..2493189 | - | 1092 | WP_041182166.1 | ribonuclease D | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | flank | IS/Tn | - | - | 2485755..2486957 | 1202 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 84 a.a. Molecular weight: 9603.92 Da Isoelectric Point: 9.9718
>T144344 WP_229001948.1 NZ_CP046495:2488708-2488959 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY
Download Length: 252 bp
>T144344 NZ_CP061914:c51377-50952 [Escherichia coli]
ATGAAAATTATTCCTGCAACGACGCTGCGGGCGACGACGTCATATCTGTCGCCCGTCGTGGTCTGGCAAATATTACTGGC
CCGCCTGCTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACGCATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAGTTGATCCGTATCGACAGGAAAGTATTT
AGCTGGCAGGAACAGACGCCTTATCTTCGTGCGGTCGATGTTTTACGGGCGCGACAGGCGACCGGCCTGCGGATTCAGTG
CAAAAACACGAATATAATCAGCCGGATGGCTGATTCAAGACATGATAAAAGACTTTACCAGCGCACGTTTAAAGCGTGCA
AGAGATGTTATTATACTAAAACATAA
ATGAAAATTATTCCTGCAACGACGCTGCGGGCGACGACGTCATATCTGTCGCCCGTCGTGGTCTGGCAAATATTACTGGC
CCGCCTGCTGGAGCAGCACTACGGGCTGAATCTTAATGACACACCATTCAACAATGAAAAGGTGATTCAGGAACGCATAG
ACGCCGGGATCACTCTGGTCGATGCCGTCAATTTTCTGGTGGAGAAGTACGAGTTGATCCGTATCGACAGGAAAGTATTT
AGCTGGCAGGAACAGACGCCTTATCTTCGTGCGGTCGATGTTTTACGGGCGCGACAGGCGACCGGCCTGCGGATTCAGTG
CAAAAACACGAATATAATCAGCCGGATGGCTGATTCAAGACATGATAAAAGACTTTACCAGCGCACGTTTAAAGCGTGCA
AGAGATGTTATTATACTAAAACATAA
Antitoxin
Download Length: 93 a.a. Molecular weight: 10826.11 Da Isoelectric Point: 4.9736
>AT144344 WP_011408759.1 NZ_CP046495:2488403-2488681 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK
Download Length: 279 bp
>AT144344 NZ_CP061914:c51743-51408 [Escherichia coli]
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGACTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGGTGAACTCTCCCCCTGCCAACAACGT
ACCGTCACGCTATACGCCAAAGGACTAACCTGCGAAGCCGATACGCTGGGTTCCTGTGGTTACGTCTATATCGCTATTTA
TCCCACTCAACGCTGA
ATGCTGCAAAAGGACAAGGTCATGCAACAAGAATGGGGGCTTCCCTGTACCGTAACACCACGCTTCACTGCTCGACTGGT
ACAGGAAAGACATAACCTGCATTACCTGGCTGATCGGGCCGCAATCACCGGGAAATTCAGCTCCCCGGATCTGCTGCATA
TCGACCAGACTTTTCCGGTGCTGATGAAACAACTGGAGCTGAAACTGGCTGACGGTGAACTCTCCCCCTGCCAACAACGT
ACCGTCACGCTATACGCCAAAGGACTAACCTGCGAAGCCGATACGCTGGGTTCCTGTGGTTACGTCTATATCGCTATTTA
TCCCACTCAACGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|