Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1817054..1818573 Replicon chromosome
Accession NZ_CP046495
Organism Xanthomonas oryzae pv. oryzae strain IXO597

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO597_RS08720 Protein ID WP_011259680.1
Coordinates 1817650..1818573 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag IXO597_RS08715 Protein ID WP_011409027.1
Coordinates 1817054..1817653 (+) Length 200 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO597_RS08680 (IXO597_008760) 1812736..1813272 - 537 WP_011409032.1 lipocalin family protein -
IXO597_RS08690 1813542..1814009 - 468 WP_181718264.1 hypothetical protein -
IXO597_RS08695 1813990..1814280 - 291 WP_011409031.1 hypothetical protein -
IXO597_RS08700 (IXO597_008780) 1814779..1815810 + 1032 WP_151420464.1 IS630 family transposase -
IXO597_RS08705 (IXO597_008785) 1815792..1816367 - 576 WP_080493559.1 BrxE family protein -
IXO597_RS08710 (IXO597_008790) 1816399..1816689 - 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
IXO597_RS08715 (IXO597_008800) 1817054..1817653 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO597_RS08720 (IXO597_008805) 1817650..1818573 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO597_RS08725 1818653..1819123 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO597_RS08730 (IXO597_008820) 1819589..1819831 + 243 WP_011259679.1 hypothetical protein -
IXO597_RS08735 (IXO597_008825) 1820256..1820765 + 510 WP_011259678.1 hypothetical protein -
IXO597_RS08740 (IXO597_008830) 1820782..1821314 - 533 Protein_1659 protein N-lysine methyltransferase family protein -
IXO597_RS08745 (IXO597_008835) 1821334..1822710 - 1377 Protein_1660 IS5 family transposase -
IXO597_RS08750 (IXO597_008840) 1822822..1822974 - 153 Protein_1661 SAM-dependent methyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T144343 WP_011259680.1 NZ_CP046495:1817650-1818573 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T144343 NZ_CP061913:c2419179-2418922 [Dactylosporangium vinaceum]
GTGACCGGAGCGATAAGTGCCAGCGAGGCCCGCCGGAGCCTGTTTCCGCTCATCGAACGGGTCAACCAGGACCACACGCC
CATCGAGATCGTGTCGCGGCACGGCAACGCGGTCCTCGTCAGCAAGGACGACTGGGACGCCATCGTCGAGACCGACTACC
TCCTGCGGACGCCGGCCAACGCCAGGCACCTCGCGGAGAGCATCGACACGTGGCGCGCGGGGAAGGCGACCGTGCGAGAG
CTGGACCTCGACGAGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT144343 WP_011409027.1 NZ_CP046495:1817054-1817653 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT144343 NZ_CP061913:c2418925-2418665 [Dactylosporangium vinaceum]
GTGAAAATCCGGTTCACCGACGAGGGCTGGCACGACTACCTGTACTGGCAGGGGCAGGACCGCCGGACGCTCAGGCGGAT
CAACGCCCTGATCGCCGACCTCCAGCGCGACCCCGACGGCCCCGGCATCGGCAAGCCGGAGCTGCTGCGCAGCCACCTGT
CCGGCCTGCGGTCCCGCCGCATCGACGAGACCCACCGCCTCGTGTACACCGTGGAGGCCGGCGAGATCATCATCCTGGCC
TGCCGCTTCCACTACGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6


Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References