Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 3631..4124 Replicon plasmid pIXO134
Accession NZ_CP046492
Organism Xanthomonas oryzae pv. oryzae strain IXO134

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag IXO134_RS23540 Protein ID WP_015462614.1
Coordinates 3798..4124 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag IXO134_RS23535 Protein ID WP_017157755.1
Coordinates 3631..3801 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO134_RS23515 (IXO134_023625) 527..1549 + 1023 WP_075244575.1 P-type DNA transfer ATPase VirB11 -
IXO134_RS23520 (IXO134_023630) 1560..2438 + 879 WP_075244574.1 lytic transglycosylase domain-containing protein -
IXO134_RS23525 (IXO134_023635) 2563..2982 + 420 WP_075244573.1 hypothetical protein -
IXO134_RS23530 (IXO134_023640) 3059..3445 + 387 WP_075244572.1 hypothetical protein -
IXO134_RS23535 (IXO134_023645) 3631..3801 + 171 WP_017157755.1 antitoxin MazE family protein Antitoxin
IXO134_RS23540 (IXO134_023650) 3798..4124 + 327 WP_015462614.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
IXO134_RS23545 (IXO134_023655) 4193..7168 - 2976 WP_075244571.1 MobF family relaxase -
IXO134_RS23550 (IXO134_023660) 7182..8756 - 1575 WP_039587421.1 type IV secretion system DNA-binding domain-containing protein -
IXO134_RS23555 8760..8933 - 174 Protein_9 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..33695 33695


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-103)

Antitoxin

Antitoxin MazE-like

(2-54)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11676.70 Da        Isoelectric Point: 9.2550

>T144341 WP_015462614.1 NZ_CP046492:3798-4124 [Xanthomonas oryzae pv. oryzae]
MMRGDFVTIAMQGDFGKPRPALVIQADQFDAHTTVTVLPVTSTLVAAPLLRITVHPSTDNGLQKPSQVMVDKAMTVKRDK
VGRAFGRVDADALVEIERCLAVFLGIAK

Download         Length: 327 bp

>T144341 NZ_CP061913:c168720-168409 [Dactylosporangium vinaceum]
GTGATCGGATCGGAGGCAGCCAAACGCCGGCCTGTGATTGTCGTGAGCAACAACGCCGCCAACCGCAGCGCCGTGTCGCG
AGGACAGGGTGTCGTCACCATCGTCCCCGTTACCAGCAACACCGCCCGCGTGTATCCCTTCCAGGTAAGACTGCCGGCGG
ATCCGGCGATCGGCCTGAACGTCGAGTCCAAGGGCCAAGCCGAACAGGTCCGCTCGATCGACGTCGCACGCATGAGCCAA
CGGCTCGGCACACTCCCGCCGACGTTGATGCGCCAACTGGACCAGGCACTCCGACTGCACCTGGAGCTGTAG

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6518.34 Da        Isoelectric Point: 4.1476

>AT144341 WP_017157755.1 NZ_CP046492:3631-3801 [Xanthomonas oryzae pv. oryzae]
MAGLRPVQIWVPDTRRPDFAEECRRQCRLAAQADMADTDMQRFMDEALADMDGWTE

Download         Length: 171 bp

>AT144341 NZ_CP061913:c168971-168756 [Dactylosporangium vinaceum]
ATGAAGGTGAGTGTGAGCCTCCCCGCGGATGACATCGACTTCGTGGACCACTACGCCCGCGAGCGCGGCACGACCCGCTC
AGCCGTCATGCACGAGGCCGTCCAGATGCTTCGCCGCCGCGACCTCGCCATGGACTACGAGGCGGCCAACGACGAATGGG
TGTCCAGCGGCGAGGCCGAGATCTGGAACGCCGTCACCGGTGACGGCCTGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References