Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2117465..2118021 Replicon chromosome
Accession NZ_CP046491
Organism Xanthomonas oryzae pv. oryzae strain IXO134

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag IXO134_RS09895 Protein ID WP_229001948.1
Coordinates 2117770..2118021 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag IXO134_RS09890 Protein ID WP_011408759.1
Coordinates 2117465..2117743 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO134_RS09875 (IXO134_010000) 2113675..2114859 + 1185 WP_117231633.1 IS256 family transposase -
IXO134_RS09880 (IXO134_010005) 2115610..2116578 - 969 WP_011258529.1 IS5-like element ISXo1 family transposase -
IXO134_RS09885 (IXO134_010015) 2116883..2117269 + 387 WP_205421001.1 hypothetical protein -
IXO134_RS09890 (IXO134_010020) 2117465..2117743 + 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
IXO134_RS09895 (IXO134_010025) 2117770..2118021 + 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IXO134_RS09900 (IXO134_010030) 2118098..2118352 + 255 WP_198912806.1 hypothetical protein -
IXO134_RS09905 2118345..2118479 + 135 WP_011051575.1 hypothetical protein -
IXO134_RS09910 (IXO134_010035) 2118548..2118802 + 255 WP_223293127.1 hypothetical protein -
IXO134_RS09915 (IXO134_010040) 2119019..2119138 + 120 Protein_1901 IS3 family transposase -
IXO134_RS09920 2119107..2119235 + 129 WP_012444694.1 hypothetical protein -
IXO134_RS09930 (IXO134_010055) 2119666..2120067 - 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
IXO134_RS09935 (IXO134_010060) 2120289..2120465 + 177 Protein_1904 DUF3606 domain-containing protein -
IXO134_RS09940 (IXO134_010070) 2120747..2121084 + 338 Protein_1905 ATP-dependent DNA ligase -
IXO134_RS09945 (IXO134_010075) 2121160..2122251 - 1092 WP_041182166.1 ribonuclease D -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T144338 WP_229001948.1 NZ_CP046491:2117770-2118021 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T144338 NZ_CP061870:c2083996-2083880 [Bacillus subtilis]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT144338 WP_011408759.1 NZ_CP046491:2117465-2117743 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT144338 NZ_CP061870:2083734-2083885 [Bacillus subtilis]
TTTCTTTAATGAGAAATGCATAAAATAAAAAGACCAGGGTGTTGGCGCACCCCGGCTCTGTACAAAAAGCTGCCCGTCAA
AGGGCTTGCTCGATGTTCAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References