Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1590253..1591772 Replicon chromosome
Accession NZ_CP046491
Organism Xanthomonas oryzae pv. oryzae strain IXO134

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO134_RS07625 Protein ID WP_011259680.1
Coordinates 1590849..1591772 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag IXO134_RS07620 Protein ID WP_011409027.1
Coordinates 1590253..1590852 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO134_RS07585 (IXO134_007635) 1585921..1586457 - 537 WP_024743012.1 lipocalin family protein -
IXO134_RS07595 1586834..1587208 - 375 WP_237384745.1 hypothetical protein -
IXO134_RS07600 1587189..1587479 - 291 WP_011409031.1 hypothetical protein -
IXO134_RS07605 (IXO134_007655) 1587978..1589009 + 1032 WP_263115185.1 IS630 family transposase -
IXO134_RS07610 (IXO134_007660) 1588991..1589566 - 576 WP_080493559.1 BrxE family protein -
IXO134_RS07615 (IXO134_007665) 1589598..1589888 - 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
IXO134_RS07620 (IXO134_007675) 1590253..1590852 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO134_RS07625 (IXO134_007680) 1590849..1591772 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO134_RS07630 1591852..1592322 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO134_RS07635 (IXO134_007695) 1592788..1593030 + 243 WP_011259679.1 hypothetical protein -
IXO134_RS07640 (IXO134_007700) 1593455..1593964 + 510 WP_011259678.1 hypothetical protein -
IXO134_RS07645 (IXO134_007705) 1593981..1594513 - 533 Protein_1460 protein N-lysine methyltransferase family protein -
IXO134_RS07650 (IXO134_007710) 1594533..1595909 - 1377 Protein_1461 IS5 family transposase -
IXO134_RS07655 (IXO134_007715) 1596021..1596173 - 153 Protein_1462 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T144337 WP_011259680.1 NZ_CP046491:1590849-1591772 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T144337 NZ_CP061870:c1628456-1627710 [Bacillus subtilis]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATCGTGGCCGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCAAAGGTCAAAGAAAAAATGTCCGCCATCCGGAAAACTTGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGAACGGTATCTCATTGTCGCAGTCAGTTTTGCTTTGATTGATGCTTTT
ATCTTCTTAAGTGCATACGTCAAAAAACTGGCCGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGTATTGATAAGCTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCTTCTCTT
TGCCACTATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAGTGGTTCTCATCCCTTTTACCATCGAGACACAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGTTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT144337 WP_011409027.1 NZ_CP046491:1590253-1590852 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT144337 NZ_CP061870:c1627710-1627540 [Bacillus subtilis]
ATGGAACGTGCGTTTCAAAACAGATGCGAGCCCAGAGCGGCGAAGCCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCATACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References