144336

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 431475..431825 Replicon chromosome
Accession NZ_CP046491
Organism Xanthomonas oryzae pv. oryzae strain IXO134

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO134_RS02020 Protein ID WP_011257368.1
Coordinates 431691..431825 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO134_RS02015 Protein ID WP_011407410.1
Coordinates 431475..431627 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO134_RS01990 (IXO134_001995) 427746..428429 - 684 WP_011257363.1 dTMP kinase -
IXO134_RS01995 428909..429451 - 543 Protein_382 GTPase -
IXO134_RS02000 (IXO134_002010) 429448..429912 - 465 Protein_383 hypothetical protein -
IXO134_RS02005 429904..430122 - 219 Protein_384 hypothetical protein -
IXO134_RS02010 (IXO134_002015) 430444..431367 + 924 WP_011407409.1 arginase -
IXO134_RS02015 (IXO134_002020) 431475..431627 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO134_RS02020 (IXO134_002025) 431691..431825 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO134_RS02025 (IXO134_002030) 432069..432278 + 210 WP_011407411.1 CsbD family protein -
IXO134_RS02030 (IXO134_002035) 432447..433736 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO134_RS02035 (IXO134_002040) 433867..434811 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T144336 WP_011257368.1 NZ_CP046491:431691-431825 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T144336 NZ_CP061870:787165-787515 [Bacillus subtilis]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
TTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCACAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATCGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT144336 WP_011407410.1 NZ_CP046491:431475-431627 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT144336 NZ_CP061870:786879-787160 [Bacillus subtilis]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGAACAACTCGTCACAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAATATTTCTTCTGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References