Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
| Location | 1543051..1544570 | Replicon | chromosome |
| Accession | NZ_CP046488 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain IXO35 | ||
Toxin (Protein)
| Gene name | rlegT | Uniprot ID | A0A0K0GMB6 |
| Locus tag | IXO35_RS07380 | Protein ID | WP_011259680.1 |
| Coordinates | 1543647..1544570 (+) | Length | 308 a.a. |
Antitoxin (Protein)
| Gene name | rlegA | Uniprot ID | A0A854CLN1 |
| Locus tag | IXO35_RS07375 | Protein ID | WP_011409027.1 |
| Coordinates | 1543051..1543650 (+) | Length | 200 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| IXO35_RS07340 (IXO35_007375) | 1538719..1539255 | - | 537 | WP_024743012.1 | lipocalin family protein | - |
| IXO35_RS07350 | 1539632..1540006 | - | 375 | WP_237384745.1 | hypothetical protein | - |
| IXO35_RS07355 | 1539987..1540277 | - | 291 | WP_011409031.1 | hypothetical protein | - |
| IXO35_RS07360 (IXO35_007395) | 1540776..1541807 | + | 1032 | WP_117231631.1 | IS630 family transposase | - |
| IXO35_RS07365 (IXO35_007400) | 1541789..1542364 | - | 576 | WP_080493559.1 | BrxE family protein | - |
| IXO35_RS07370 (IXO35_007405) | 1542396..1542668 | - | 273 | WP_230455482.1 | FaeA/PapI family transcriptional regulator | - |
| IXO35_RS07375 (IXO35_007415) | 1543051..1543650 | + | 600 | WP_011409027.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| IXO35_RS07380 (IXO35_007420) | 1543647..1544570 | + | 924 | WP_011259680.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| IXO35_RS07385 | 1544650..1545120 | - | 471 | WP_228329666.1 | helix-turn-helix domain-containing protein | - |
| IXO35_RS07390 (IXO35_007435) | 1545586..1545828 | + | 243 | WP_011259679.1 | hypothetical protein | - |
| IXO35_RS07395 (IXO35_007440) | 1546253..1546762 | + | 510 | WP_011259678.1 | hypothetical protein | - |
| IXO35_RS07400 (IXO35_007445) | 1546779..1547311 | - | 533 | Protein_1411 | protein N-lysine methyltransferase family protein | - |
| IXO35_RS07405 (IXO35_007450) | 1547331..1548707 | - | 1377 | Protein_1412 | IS5 family transposase | - |
| IXO35_RS07410 (IXO35_007455) | 1548819..1548971 | - | 153 | Protein_1413 | SAM-dependent methyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 308 a.a. Molecular weight: 34114.16 Da Isoelectric Point: 5.4588
>T144332 WP_011259680.1 NZ_CP046488:1543647-1544570 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA
Download Length: 924 bp
>T144332 NZ_CP061853:480387-480737 [Bacillus amyloliquefaciens]
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG
TTGATTGTAAAGCGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGCGTACGCCCGGT
TTTAGTGATCCAAAATGATATCGGAAATCGCTTTAGCCCGACTGCTATTGTTGCAGCCATAACAGCCCAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATTGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGATTAACGGATAAAATAACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCCT
GCAAATCAGTTTGGCACTCATTGATTTTTAG
Antitoxin
Download Length: 200 a.a. Molecular weight: 22037.74 Da Isoelectric Point: 10.1240
>AT144332 WP_011409027.1 NZ_CP046488:1543051-1543650 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA
Download Length: 600 bp
>AT144332 NZ_CP061853:480100-480381 [Bacillus amyloliquefaciens]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACTTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCGTATGTCAGCGAACGGACAACTCGCCATAACC
GTGATTTGATGAGACGCGGGTATATGGAAATGGCGAAAATCAACTTGAATATCTCTTCTGAGGCTCACTATGCTGAGTGC
GAAGCAGAAACGACCGTTGAGCGCTTAGTCAGCGGAGGATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A0K0GMB6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A854CLN1 |