144331

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 429170..429520 Replicon chromosome
Accession NZ_CP046488
Organism Xanthomonas oryzae pv. oryzae strain IXO35

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO35_RS02025 Protein ID WP_011257368.1
Coordinates 429386..429520 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO35_RS02020 Protein ID WP_011407410.1
Coordinates 429170..429322 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO35_RS01995 (IXO35_002000) 425441..426124 - 684 WP_011257363.1 dTMP kinase -
IXO35_RS02000 426604..427146 - 543 Protein_383 GTPase -
IXO35_RS02005 (IXO35_002015) 427143..427607 - 465 Protein_384 hypothetical protein -
IXO35_RS02010 427599..427817 - 219 Protein_385 hypothetical protein -
IXO35_RS02015 (IXO35_002020) 428139..429062 + 924 WP_011407409.1 arginase -
IXO35_RS02020 (IXO35_002025) 429170..429322 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO35_RS02025 (IXO35_002030) 429386..429520 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO35_RS02030 (IXO35_002035) 429764..429973 + 210 WP_011407411.1 CsbD family protein -
IXO35_RS02035 (IXO35_002040) 430142..431431 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO35_RS02040 (IXO35_002045) 431562..432506 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T144331 WP_011257368.1 NZ_CP046488:429386-429520 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T144331 NZ_CP061852:c1257919-1257173 [Bacillus amyloliquefaciens]
ATGCTTTTGTTTTTTCAGATCATGGTGTGGACGATGGCGGCCGCACTCATTTTATATGTGTACGCATCCTGGCGGTATGA
GGCAAAGGTAAAAGAAAAAATGTTTGCCATCCGTAAAACGTGGTATTTACTATTTGTACTGGGCTCCATGGTCTATTGGA
CATATGATCCCGAATCGCTCTTTGCCGCATGGAGACAATATTTGATTGTTGCCGTCTGCTTTGCCCTTATTGATGCGTTT
ATCTTTTTGAGCGCGTATATCAAAAAGCTCGCCGGCAATGAATTAGAGACGGATACGCGGGAAATTTTAGAAGAAAATAA
CGAAATGCTTCACTCCTATCTTGAAAAACTGAAAACCTATCAATATCTGTTGAAAAATGAACCGATCCATGTATATTATG
GAAGTACAGAAGCTTATGCGGAAGGCATCAGCAGACTGCTGGCCGCTTATGCCGAAAAAATGAATGTCACGGCTTCCTTG
TGCGACTATTCCGCACAATCGGATAAGGACCGCTTGACGGAGCATATGCCTGATGCGGCGGACGTTCAGTCCCGTCTTAA
CCGTAAAGACGTCTACTATGATCAAAAAGGCAGGCTTGTGCTTATTCCGTTTACAGTCCAGAACCGCCATTACGTGATCA
AACTCACGTCGGAAAACCTGTTGACGGAATTCGATTATTTGCTTTTCACATCGCTAACGAGCATTTATGATTTAATGCTG
CCAATAGAAGAGGAAGGTGACGGTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT144331 WP_011407410.1 NZ_CP046488:429170-429322 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT144331 NZ_CP061852:c1257172-1257002 [Bacillus amyloliquefaciens]
ATGGAGCAGGCATTTCAAAACGGGCAGCCGGAACAAAGAGCGAAACCGTTCAAAATGTTTAAAAAACGTTCAATGACAAG
TATCGCAAGTTACCAGGTCAGCCCTCATACCGCCAGAATTTTCAAAGAAAACGAGCGGCTGATTGACAAGTATAAACAAA
AAAAAGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References