Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3349512..3351031 Replicon chromosome
Accession NZ_CP046479
Organism Xanthomonas oryzae pv. oryzae strain IXO842

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag IXO842_RS15595 Protein ID WP_011259680.1
Coordinates 3349512..3350435 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0K0GMG7
Locus tag IXO842_RS15600 Protein ID WP_012445456.1
Coordinates 3350432..3351031 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO842_RS15565 (IXO842_015570) 3345111..3345263 + 153 Protein_2971 SAM-dependent methyltransferase -
IXO842_RS15570 (IXO842_015575) 3345375..3346751 + 1377 Protein_2972 IS5 family transposase -
IXO842_RS15575 (IXO842_015580) 3346771..3347303 + 533 Protein_2973 protein N-lysine methyltransferase family protein -
IXO842_RS15580 (IXO842_015585) 3347320..3347829 - 510 WP_011259678.1 hypothetical protein -
IXO842_RS15585 (IXO842_015590) 3348254..3348496 - 243 WP_011259679.1 hypothetical protein -
IXO842_RS15590 3348962..3349432 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
IXO842_RS15595 (IXO842_015605) 3349512..3350435 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
IXO842_RS15600 (IXO842_015610) 3350432..3351031 - 600 WP_012445456.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
IXO842_RS15605 (IXO842_015620) 3351396..3351686 + 291 WP_229002604.1 FaeA/PapI family transcriptional regulator -
IXO842_RS15610 (IXO842_015625) 3351718..3352206 + 489 WP_027703988.1 BrxE family protein -
IXO842_RS15615 (IXO842_015630) 3352193..3352471 - 279 Protein_2981 transposase -
IXO842_RS15620 (IXO842_015635) 3352597..3353565 - 969 WP_011258529.1 IS5-like element ISXo1 family transposase -
IXO842_RS15625 (IXO842_015640) 3353638..3354151 - 514 Protein_2983 IS5 family transposase -
IXO842_RS15630 (IXO842_015645) 3354287..3355320 - 1034 Protein_2984 IS630 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T144329 WP_011259680.1 NZ_CP046479:c3350435-3349512 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T144329 NZ_CP061850:c6451393-6451112 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACACCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCTCTGAAAGCCGTTCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCGTTTCGGGTTAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22051.76 Da        Isoelectric Point: 10.1240

>AT144329 WP_012445456.1 NZ_CP046479:c3351031-3350432 [Xanthomonas oryzae pv. oryzae]
MDTTIDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT144329 NZ_CP061850:c6451617-6451390 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCCTACCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACATCGAGATCGAGAAGCGCTGGGGGCTGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A0K0GMG7

References