Detailed information of TA system TA144328

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2164412..2164968
• Replicon: chromosome
• Accession: NZ_CP046479
• Organism: Xanthomonas oryzae pv. oryzae strain IXO842

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: IXO842_RS10255
• Protein ID: WP_229001948.1
• Coordinates: 2164717..2164968 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: IXO842_RS10250
• Protein ID: WP_011408759.1
• Coordinates: 2164412..2164690 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IXO842_RS10235 (IXO842_010195)	2160596..2161831	+	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
IXO842_RS10240 (IXO842_010200)	2162160..2163395	-	1236	WP_011257310.1	ISL3-like element ISXoo13 family transposase	-
IXO842_RS10245 (IXO842_010210)	2163872..2164216	+	345	WP_199285675.1	hypothetical protein	-
IXO842_RS10250 (IXO842_010215)	2164412..2164690	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
IXO842_RS10255 (IXO842_010220)	2164717..2164968	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IXO842_RS10260 (IXO842_010225)	2165045..2165299	+	255	WP_198912806.1	hypothetical protein	-
IXO842_RS10265	2165292..2165426	+	135	WP_011051575.1	hypothetical protein	-
IXO842_RS10270 (IXO842_010230)	2165495..2165749	+	255	WP_223293127.1	hypothetical protein	-
IXO842_RS10275 (IXO842_010235)	2165966..2166085	+	120	Protein_1957	IS3 family transposase	-
IXO842_RS10280	2166054..2166182	+	129	WP_012444694.1	hypothetical protein	-
IXO842_RS10290 (IXO842_010250)	2166613..2167014	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
IXO842_RS10295 (IXO842_010255)	2167236..2167412	+	177	Protein_1960	DUF3606 domain-containing protein	-
IXO842_RS10300 (IXO842_010265)	2167694..2168010	+	317	Protein_1961	ATP-dependent DNA ligase	-
IXO842_RS10305 (IXO842_010270)	2168107..2169198	-	1092	WP_075239568.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T144328 WP_229001948.1 NZ_CP046479:2164717-2164968 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T144328 NZ_CP061850:c5154857-5154579 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTTGCAATGCTTCATGCGGCTACGGAGCTTCGAGACCTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT144328 WP_011408759.1 NZ_CP046479:2164412-2164690 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT144328 NZ_CP061850:c5154567-5154262 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCAAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2