Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 419199..419549 Replicon chromosome
Accession NZ_CP046479
Organism Xanthomonas oryzae pv. oryzae strain IXO842

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag IXO842_RS01970 Protein ID WP_011257368.1
Coordinates 419415..419549 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag IXO842_RS01965 Protein ID WP_011407410.1
Coordinates 419199..419351 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IXO842_RS01940 (IXO842_001930) 415470..416153 - 684 WP_011257363.1 dTMP kinase -
IXO842_RS01945 416633..417175 - 543 Protein_372 GTPase -
IXO842_RS01950 (IXO842_001945) 417172..417636 - 465 Protein_373 hypothetical protein -
IXO842_RS01955 417628..417846 - 219 Protein_374 hypothetical protein -
IXO842_RS01960 (IXO842_001950) 418168..419091 + 924 WP_011407409.1 arginase -
IXO842_RS01965 (IXO842_001955) 419199..419351 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
IXO842_RS01970 (IXO842_001960) 419415..419549 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
IXO842_RS01975 (IXO842_001965) 419793..420002 + 210 WP_011407411.1 CsbD family protein -
IXO842_RS01980 (IXO842_001970) 420171..421460 + 1290 WP_011257370.1 tryptophan--tRNA ligase -
IXO842_RS01985 (IXO842_001975) 421591..422535 + 945 WP_041181936.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T144327 WP_011257368.1 NZ_CP046479:419415-419549 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T144327 NZ_CP061850:c4927148-4926849 [Pseudomonas aeruginosa]
ATGGTCGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT144327 WP_011407410.1 NZ_CP046479:419199-419351 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT144327 NZ_CP061850:c4926852-4926562 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGACAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References