Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3838643..3839303 Replicon chromosome
Accession NZ_CP046446
Organism Leclercia sp. J807

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag GNG26_RS18155 Protein ID WP_156239713.1
Coordinates 3838643..3839056 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag GNG26_RS18160 Protein ID WP_103176875.1
Coordinates 3839037..3839303 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNG26_RS18135 3834646..3836379 - 1734 WP_156239711.1 single-stranded-DNA-specific exonuclease RecJ -
GNG26_RS18140 3836385..3837098 - 714 WP_156239712.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
GNG26_RS18145 3837120..3838016 - 897 WP_103822768.1 site-specific tyrosine recombinase XerD -
GNG26_RS18150 3838117..3838638 + 522 WP_103176873.1 flavodoxin FldB -
GNG26_RS18155 3838643..3839056 - 414 WP_156239713.1 protein YgfX Toxin
GNG26_RS18160 3839037..3839303 - 267 WP_103176875.1 FAD assembly factor SdhE Antitoxin
GNG26_RS18165 3839606..3840586 + 981 WP_156239714.1 tRNA-modifying protein YgfZ -
GNG26_RS18170 3840672..3841331 - 660 WP_156239715.1 hemolysin III family protein -
GNG26_RS18175 3841497..3841808 - 312 WP_114316856.1 N(4)-acetylcytidine aminohydrolase -
GNG26_RS18180 3841861..3842592 + 732 WP_156240209.1 MurR/RpiR family transcriptional regulator -
GNG26_RS18185 3842707..3844140 + 1434 WP_156239716.1 6-phospho-beta-glucosidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16222.04 Da        Isoelectric Point: 10.7511

>T144310 WP_156239713.1 NZ_CP046446:c3839056-3838643 [Leclercia sp. J807]
VVLWQSDLRVSWRAQWMSLLLHGLVAAVILLMPWPLSYTPLWLMLLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWQDS
EWEIVGTPWMLNSGMMLRLRKGAGQRCHHLWLAADSMDEAEWRDLRRMMSHQPTQGR

Download         Length: 414 bp

>T144310 NZ_CP061846:2418801-2419193 [Chryseoglobus sp. 28M-23]
GTGGCGCTGTACTTCGACACATCCGCACTCGTGAAGCTCGTCGTCGCAGAACCTGAGACGACCGCCTTGCGAGACGCCGC
GCGCGTATCGACGGTCGAACCCGTCAGCAGCGACCTCACGCGAACCGAGCTCCTTCGCACGGTTCGTCGCGGTGCTCCAG
ACCGCCTGGTATCGGCACGTGAAGTGCTCGAGGCGCTCACACTCGTACCGGTGACGACCGAAGTGTGTGAAGCGGCCGGG
AGGCTCGAACCTCGAACACTGCGTGCTCTCGATGCTCTGCACCTGGCTTCAGCGCTGGGCCTCGGGGACGATCTGGAGGC
CGTCGTCACGTACGACCACCGCCTCGCCGACGCGTGCCGCGCGAACGGTGTCGCGGTGCTCGCGCCGCACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10503.97 Da        Isoelectric Point: 4.8382

>AT144310 WP_103176875.1 NZ_CP046446:c3839303-3839037 [Leclercia sp. J807]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKHLFVRLLENDDPDLFNWLMNHGKPADAELQRMVLLIQTRN
QERGPVAI

Download         Length: 267 bp

>AT144310 NZ_CP061846:2418534-2418797 [Chryseoglobus sp. 28M-23]
ATGGCAGAAGTCGGAATTCGAGCGCTCAAGCAGAACGCGTCCGCGGTGGTGGCCGACGCGGCTGCCGGCGAGACGGTCAC
GATCACTGATCGTGGTCGCCCGGTGGCGCAGCTGACCTCGATCGCGGCATCGCCACTGCAGCGCATGCTGGCCAACGGCA
CGGCGCGCCGTGCGCGTCGCGACCTCGCCTCGCTTCCCGCGCCAACCGAGGCCCCGCCTCTGACTCCCGTCCTGGCCGAG
ATCCGCGACGACGAGCGCTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References