Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 566072..566636 Replicon chromosome
Accession NZ_CP046446
Organism Leclercia sp. J807

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GNG26_RS02655 Protein ID WP_114315981.1
Coordinates 566331..566636 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GNG26_RS02650 Protein ID WP_114315982.1
Coordinates 566072..566344 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNG26_RS02620 561162..561905 - 744 WP_156237695.1 AraC family transcriptional regulator -
GNG26_RS02625 562091..562483 + 393 WP_156237696.1 Rhs-Related protein -
GNG26_RS02630 562461..562881 + 421 Protein_506 hypothetical protein -
GNG26_RS02635 562887..563066 + 180 WP_103823120.1 hypothetical protein -
GNG26_RS02640 563630..565000 + 1371 WP_103178115.1 NAD-dependent succinate-semialdehyde dehydrogenase -
GNG26_RS02645 565099..565644 - 546 WP_156237697.1 porin -
GNG26_RS02650 566072..566344 + 273 WP_114315982.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GNG26_RS02655 566331..566636 + 306 WP_114315981.1 type II toxin-antitoxin system YafQ family toxin Toxin
GNG26_RS02660 566710..567663 - 954 WP_156237698.1 GTPase -
GNG26_RS02665 567674..567877 - 204 WP_032616354.1 YbdD/YjiX family protein -
GNG26_RS02670 567944..570097 - 2154 WP_156237699.1 carbon starvation protein A -
GNG26_RS02675 570315..571202 - 888 WP_156237700.1 WYL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(13-101)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-69)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11530.14 Da        Isoelectric Point: 7.4643

>T144297 WP_114315981.1 NZ_CP046446:566331-566636 [Leclercia sp. J807]
MGKSKRAPLPFRSDYTKTFVKAWERYNKAGRRDMHDTAAIMSLVLSGNPIPAEYSDHALTGDMQGFRELHIGGDYLLIYR
VDDKKHLVVFTDLGTHAELFE

Download         Length: 306 bp

>T144297 NZ_CP061842:797401-797811 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10206.54 Da        Isoelectric Point: 5.8874

>AT144297 WP_114315982.1 NZ_CP046446:566072-566344 [Leclercia sp. J807]
MDSVIRSRIDSELKARAGDVLESCGLNWSTAIRLFAEQIVKNEGIPFEVTRKPTTRLRNAMREAEEISTHQNGRFDGVEQ
LMESLKNGKE

Download         Length: 273 bp

>AT144297 NZ_CP061842:797154-797420 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References