Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 616906..617470 Replicon chromosome
Accession NZ_CP046445
Organism Leclercia sp. 119287

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GNG27_RS02985 Protein ID WP_156262834.1
Coordinates 617165..617470 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GNG27_RS02980 Protein ID WP_106995684.1
Coordinates 616906..617178 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GNG27_RS02955 612342..612683 + 342 WP_156262831.1 hypothetical protein -
GNG27_RS02960 612799..613266 + 468 WP_156262832.1 MarR family transcriptional regulator -
GNG27_RS02965 613266..614333 + 1068 WP_142488090.1 HlyD family secretion protein -
GNG27_RS02970 614339..615406 + 1068 WP_156262833.1 DUF2955 domain-containing protein -
GNG27_RS02975 615410..616690 - 1281 WP_142488092.1 DUF445 domain-containing protein -
GNG27_RS02980 616906..617178 + 273 WP_106995684.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GNG27_RS02985 617165..617470 + 306 WP_156262834.1 type II toxin-antitoxin system YafQ family toxin Toxin
GNG27_RS02990 617508..618164 - 657 WP_156262835.1 LysE family translocator -
GNG27_RS02995 618212..618955 - 744 WP_156262836.1 AraC family transcriptional regulator -
GNG27_RS03000 619115..619537 + 423 WP_156262837.1 hypothetical protein -
GNG27_RS03005 619980..620672 + 693 WP_156262838.1 hypothetical protein -
GNG27_RS03010 620923..621402 + 480 WP_156262839.1 type VI secretion system tube protein Hcp -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(11-101)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-66)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.20 Da        Isoelectric Point: 7.4630

>T144276 WP_156262834.1 NZ_CP046445:617165-617470 [Leclercia sp. 119287]
MGKSKRAPLPYRSDYTKTFVKAWERYNKAGRRDMHATAEIMSLVLSGNPIPSEYSDHPLTGDMQGFRELHIGGDYLLVYR
IDDKKHLVVFTDLGTHAELFE

Download         Length: 306 bp

>T144276 NZ_CP061828:c3652377-3651988 [Acinetobacter seifertii]
TTGATCAACCAATTGAATTTTAAACTGAAATATAGCCGTTTCGCGATTGTATTTCAGTTTTTTATTGGCCTATGTTTAGC
AGCTCTGTTTTATCAGCTGATACCAATACTCTGGTGGTTGGTTACGCTCTGTTTATTATTTATAAGTTTTATTTTCTTTT
TAAAGCGACCACAGCTCGTTCAAATTGCCTATTTAGATCAGAAATTATGGTCTCTTAGCTTTCATTCAGAACAAACCATT
TCTCGTGTAGAAATTTTAAAAATAATTGATTATCAGATTTTCATAGTGGTCTATTTTAAGGGTGATAAAACATTAACTTC
TGTTATTTGGTTTGATCAAATGTCCTTATCTCAATGGAAACAGCTTAAGACTTTAGAAAAATTCTATTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10066.30 Da        Isoelectric Point: 4.8483

>AT144276 WP_106995684.1 NZ_CP046445:616906-617178 [Leclercia sp. 119287]
MDSVIRSRIDSELKAQAGSVLESCGLTWSTAIRLFAEQIVKNEGIPFEVTRKPTARLRNAMREAEDISTHQNGRFDGVDQ
LMESLNDGKE

Download         Length: 273 bp

>AT144276 NZ_CP061828:c3652629-3652384 [Acinetobacter seifertii]
ATGACCTTGGAAGAACGTAAAGTAGTTTATCGCGCACGCCGCGGTTTAAAGGAAATTGATGTCTATTTTGACCCGTATGT
GAAAAATTATTATTTAAAGGCAGATCCAGCAGAAAAAGCATTGTTTGCTGAATTAGTAGAGCAGGAAGATCCTGATTTAC
TTGACTGGTTTATGGAAGTATCTGAACCGCCGCGTACAGAATTACGTGATTTTATTCATAAATTAAAGCATTATGTTCAT
GGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References