Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/HicA-HicB |
| Location | 1669974..1670605 | Replicon | chromosome |
| Accession | NZ_CP046444 | ||
| Organism | Granulicella sp. 5B5 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | GOB94_RS07035 | Protein ID | WP_182278125.1 |
| Coordinates | 1669974..1670162 (+) | Length | 63 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | GOB94_RS07040 | Protein ID | WP_182278126.1 |
| Coordinates | 1670183..1670605 (+) | Length | 141 a.a. |
Genomic Context
Location: 1667484..1667909 (426 bp)
Type: Others
Protein ID: WP_182278122.1
Type: Others
Protein ID: WP_182278122.1
Location: 1668343..1668906 (564 bp)
Type: Others
Protein ID: WP_182278489.1
Type: Others
Protein ID: WP_182278489.1
Location: 1668903..1669373 (471 bp)
Type: Others
Protein ID: WP_182278123.1
Type: Others
Protein ID: WP_182278123.1
Location: 1669433..1669849 (417 bp)
Type: Others
Protein ID: WP_182278124.1
Type: Others
Protein ID: WP_182278124.1
Location: 1669974..1670162 (189 bp)
Type: Toxin
Protein ID: WP_182278125.1
Type: Toxin
Protein ID: WP_182278125.1
Location: 1670183..1670605 (423 bp)
Type: Antitoxin
Protein ID: WP_182278126.1
Type: Antitoxin
Protein ID: WP_182278126.1
Location: 1673381..1673992 (612 bp)
Type: Others
Protein ID: WP_182278128.1
Type: Others
Protein ID: WP_182278128.1
Location: 1666241..1666411 (171 bp)
Type: Others
Protein ID: WP_182278120.1
Type: Others
Protein ID: WP_182278120.1
Location: 1666542..1667291 (750 bp)
Type: Others
Protein ID: WP_182278121.1
Type: Others
Protein ID: WP_182278121.1
Location: 1670626..1673094 (2469 bp)
Type: Others
Protein ID: WP_182278127.1
Type: Others
Protein ID: WP_182278127.1
Location: 1674063..1674290 (228 bp)
Type: Others
Protein ID: WP_182278129.1
Type: Others
Protein ID: WP_182278129.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GOB94_RS07005 | 1666241..1666411 | - | 171 | WP_182278120.1 | hypothetical protein | - |
| GOB94_RS07010 | 1666542..1667291 | - | 750 | WP_182278121.1 | glucose 1-dehydrogenase | - |
| GOB94_RS07015 | 1667484..1667909 | + | 426 | WP_182278122.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| GOB94_RS07020 | 1668343..1668906 | + | 564 | WP_182278489.1 | SRPBCC domain-containing protein | - |
| GOB94_RS07025 | 1668903..1669373 | + | 471 | WP_182278123.1 | SRPBCC domain-containing protein | - |
| GOB94_RS07030 | 1669433..1669849 | + | 417 | WP_182278124.1 | VOC family protein | - |
| GOB94_RS07035 | 1669974..1670162 | + | 189 | WP_182278125.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| GOB94_RS07040 | 1670183..1670605 | + | 423 | WP_182278126.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| GOB94_RS07045 | 1670626..1673094 | - | 2469 | WP_182278127.1 | glucan 1,4-alpha-glucosidase | - |
| GOB94_RS07050 | 1673381..1673992 | + | 612 | WP_182278128.1 | superoxide dismutase | - |
| GOB94_RS07055 | 1674063..1674290 | - | 228 | WP_182278129.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 63 a.a. Molecular weight: 6994.19 Da Isoelectric Point: 11.1572
>T144268 WP_182278125.1 NZ_CP046444:1669974-1670162 [Granulicella sp. 5B5]
MSSRELIQALIRDGWFEVAHAGSHKQFKHATKPGRVTVPYPKRDLPLGTLKSIEKQAGLKLR
MSSRELIQALIRDGWFEVAHAGSHKQFKHATKPGRVTVPYPKRDLPLGTLKSIEKQAGLKLR
Download Length: 189 bp
>T144268 NZ_CP061801:c3987064-3986687 [Enterobacter mori]
ATGCAAACACAACCTGTTCCCCCGACACAGGAGGCTTCACCACGCCCGTCACCAGTGGAGATCTGGCTCCGCCTTTTGAG
TCACCTGCTGGACCGTCACTACGGTCTGACGTTAAACGACACGCCATTTTGCAATGATGGTGTGATCCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGCCCTGATACGCACCGATCGTCACGGTTTC
AGCGCAGAAACACAGTCCCCACTCATCAGCAGTATTGATATCCTTCGCGCCCGTAAGGCCTGTGGACTGATGGCACGCAA
TGGCTACAGACTGGTGACCGATATCACCACCGGCAAATACAGCGAGGTGACTCGATGA
ATGCAAACACAACCTGTTCCCCCGACACAGGAGGCTTCACCACGCCCGTCACCAGTGGAGATCTGGCTCCGCCTTTTGAG
TCACCTGCTGGACCGTCACTACGGTCTGACGTTAAACGACACGCCATTTTGCAATGATGGTGTGATCCAGGAGCATATCG
ACGCCGGTATCTCACTGTGCGACGCGGTGAATTTTATCGTGGAGAAATACGCCCTGATACGCACCGATCGTCACGGTTTC
AGCGCAGAAACACAGTCCCCACTCATCAGCAGTATTGATATCCTTCGCGCCCGTAAGGCCTGTGGACTGATGGCACGCAA
TGGCTACAGACTGGTGACCGATATCACCACCGGCAAATACAGCGAGGTGACTCGATGA
Antitoxin
Download Length: 141 a.a. Molecular weight: 15458.67 Da Isoelectric Point: 8.9222
>AT144268 WP_182278126.1 NZ_CP046444:1670183-1670605 [Granulicella sp. 5B5]
MEYIAYLHKDKGSDYGVSFPDFPGCVTAGKSLEEARRMAVEALTLHMAGMLEDGEAIPEPSTLDQLAKDPAMRGAVAFLV
SAEPPEKTVRINITARESQIETIDRLARARGMTRSAYMVQSAVRITTTRERTRGTARRRA
MEYIAYLHKDKGSDYGVSFPDFPGCVTAGKSLEEARRMAVEALTLHMAGMLEDGEAIPEPSTLDQLAKDPAMRGAVAFLV
SAEPPEKTVRINITARESQIETIDRLARARGMTRSAYMVQSAVRITTTRERTRGTARRRA
Download Length: 423 bp
>AT144268 NZ_CP061801:c3987440-3987114 [Enterobacter mori]
ATCGCCGAACCCTGGTGGGGGCTTAAACGCGATATCACACCCTGTTTTGGCGCTCGCCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTCGCCGACCGCGCCAGTATCACCGGGCAGTTCAGCGACGCGGATTTACGCCATCTGGACCAGGCATTTCCGC
TGCTGCTCAAACAGCTTGAACTGATGCTCACCAGCGGTGAACTCAATCCCCGCCATCAGCACGGCGTCACGCTCTACGCA
AAAGGGCTGACCTGCAACGCGGATACACTCGGCAGTTGCGGATATGTCTATATAGCGATTTACCCGACACCTGCAACAAC
AGAATAA
ATCGCCGAACCCTGGTGGGGGCTTAAACGCGATATCACACCCTGTTTTGGCGCTCGCCTGGTGCAGGAGGGCAACCGGCT
GCACTATCTCGCCGACCGCGCCAGTATCACCGGGCAGTTCAGCGACGCGGATTTACGCCATCTGGACCAGGCATTTCCGC
TGCTGCTCAAACAGCTTGAACTGATGCTCACCAGCGGTGAACTCAATCCCCGCCATCAGCACGGCGTCACGCTCTACGCA
AAAGGGCTGACCTGCAACGCGGATACACTCGGCAGTTGCGGATATGTCTATATAGCGATTTACCCGACACCTGCAACAAC
AGAATAA