Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 1329229..1329791 Replicon chromosome
Accession NZ_CP046444
Organism Granulicella sp. 5B5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag GOB94_RS05790 Protein ID WP_182277910.1
Coordinates 1329229..1329597 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag GOB94_RS05795 Protein ID WP_182277911.1
Coordinates 1329594..1329791 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GOB94_RS05765 1324790..1325128 - 339 WP_182277906.1 hypothetical protein -
GOB94_RS05770 1325460..1325696 + 237 WP_182277907.1 DNA gyrase inhibitor YacG -
GOB94_RS05775 1325817..1326320 + 504 WP_182278461.1 phosphatidylglycerophosphatase A -
GOB94_RS05780 1326362..1327942 + 1581 WP_182277908.1 hypothetical protein -
GOB94_RS05785 1328014..1329081 + 1068 WP_182277909.1 gluconolaconase -
GOB94_RS05790 1329229..1329597 - 369 WP_182277910.1 type II toxin-antitoxin system VapC family toxin Toxin
GOB94_RS05795 1329594..1329791 - 198 WP_182277911.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
GOB94_RS05800 1329883..1330707 + 825 WP_182277912.1 hypothetical protein -
GOB94_RS05805 1330955..1332223 + 1269 WP_182277913.1 competence/damage-inducible protein A -
GOB94_RS05810 1332415..1333047 + 633 WP_182277914.1 glycerol-3-phosphate 1-O-acyltransferase PlsY -
GOB94_RS05815 1333094..1334104 + 1011 WP_182277915.1 NAD(P)-dependent glycerol-3-phosphate dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13598.09 Da        Isoelectric Point: 10.3439

>T144267 WP_182277910.1 NZ_CP046444:c1329597-1329229 [Granulicella sp. 5B5]
VILADTSVWIDHLRGTSSALRFELEQGRIVMHPYVTAELALGSLKDRRKTVAMLEMLPQLQVAMLSEVRRMAEAHKLHGK
GIGLVDVHLIASVMITPGTSLWTVDKRLHGVAEAMRVHRTIL

Download         Length: 369 bp

>T144267 NZ_CP061801:c3803668-3803258 [Enterobacter mori]
GTGGTCCTGTGGCAATCTGATCTTCGCGTCTCGTGGCGCTCACAGTGGATGTCGTTATTACTCCACGGCCTGGTTGCGGC
ATTTATTTTACTGATGCCGTGGCCGCTTAGCTATACACCTTTGTGGCTGCTGTTGCTGTCATTTGTGGTTTTTGACAGCG
TGCGCAGCCAACGCCGAATTAACGCCTGTCAGGGTGAAATCAAATTACTGATGGACTCTCGCCTGCGCTGGCAGGGTAAA
GACTGGGATATTATTGGTATGCCCTGGATGCTCAATTCCGGCATGATGCTACGGTTGCGCAAGGTAGATGGCGGGCGTCG
CCAACATCTGTGGTTGTCAGCAGACAGCATGGACACTGCAGAGTGGCGAGATCTGCGCCGGATGATATTGCAGCAGCCGA
CGCAGGAATAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7198.37 Da        Isoelectric Point: 10.6723

>AT144267 WP_182277911.1 NZ_CP046444:c1329791-1329594 [Granulicella sp. 5B5]
MRTTLALDDELVATAQEFTGVMEKTALVREALRALIEREAARRLAALEGSMPKASAAPRRRMAER

Download         Length: 198 bp

>AT144267 NZ_CP061801:c3803915-3803649 [Enterobacter mori]
ATGGATATTAACAACAAGGCCCGTATTCACTGGGCGTGTCGACGTGGTATGCGTGAACTTGATATTTCTATCATGCCTTT
CTTCGAGTATGAGTATGACAGCCTGAGCGATGACGATAAGCGTCTGTTTGTACGCCTGCTTGAGTCTGACGATCCTGATT
TATTCAACTGGCTGATGAATCACGGTCAACCCGCCGACACCGGGTTGCAACGGATGGTGGAATTAATTCAAACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References