Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 968433..969046 Replicon chromosome
Accession NZ_CP046444
Organism Granulicella sp. 5B5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GOB94_RS04185 Protein ID WP_182277640.1
Coordinates 968433..968729 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GOB94_RS04190 Protein ID WP_182277641.1
Coordinates 968726..969046 (-) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GOB94_RS04165 963537..965852 - 2316 WP_182277636.1 N-acetylmuramoyl-L-alanine amidase -
GOB94_RS04170 966009..966593 + 585 WP_182277637.1 DUF4254 domain-containing protein -
GOB94_RS04175 966749..967354 + 606 WP_182277638.1 tetratricopeptide repeat protein -
GOB94_RS04180 967403..968443 + 1041 WP_182277639.1 YvcK family protein -
GOB94_RS04185 968433..968729 - 297 WP_182277640.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GOB94_RS04190 968726..969046 - 321 WP_182277641.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
GOB94_RS04195 969151..970395 - 1245 WP_182278429.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
GOB94_RS04200 970474..971898 - 1425 WP_182277642.1 glucosylceramidase -
GOB94_RS04205 971913..973232 + 1320 WP_182277643.1 insulinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-50)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10927.44 Da        Isoelectric Point: 4.3774

>T144266 WP_182277640.1 NZ_CP046444:c968729-968433 [Granulicella sp. 5B5]
MKAPILWSEDALADMLSTFEMISESSPRGALLVDDRVNEQIELLADFPLAGRGSRTEGTRELIIDRATCVVVYRVEGDAV
RILRVIYGGQEWRTNSSV

Download         Length: 297 bp

>T144266 NZ_CP061801:3573736-3574035 [Enterobacter mori]
ATGATTAATCATTTTCGCGATCAATGGCTTGAGGATTTTTTTCTTTATGGGAAATCGAGCAATGTGATCCCTTCTGGCCT
TGAAGCAGCTCTGGCGAGAAAGCTGGATATTATCAATGCAGCAACATCTCACCGGGATCTGCGATCGCCACCAGGCAATA
TGTACGAAACATTGAATCCTCCACTAAAGGGGTTTTCCTCAATTCGCGTTAACAGGCAATACAGGCTGGTATTCAGGTGG
GTAGAGGGTAAAGCAGACGATCTCTATCTTTCACCCCATAAATACACGCTATACAAATGA

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11753.53 Da        Isoelectric Point: 8.5538

>AT144266 WP_182277641.1 NZ_CP046444:c969046-968726 [Granulicella sp. 5B5]
MAANALVQTRIDEDIKERATAVLEKQGLTISDAVRILLTRTANEGVLPLARTPMEAAIYKGDGTDYDAWFRAKVQEALDD
PRPGVPHAEVRRRMNILREKALAKIG

Download         Length: 321 bp

>AT144266 NZ_CP061801:3574046-3574393 [Enterobacter mori]
ATGGCACTCCAACAGGCACTTCGCAAACCCACCACGCCGGGTGATGTGTTGCAGTATGAGTATCTTGAACCGCTCAATCT
GAAAATCAGCGATCTCGCGGACATGCTGAATGTGCACCGCAACACCATCAGTGCGCTGGTGAATAATAACCGTAAGCTGA
CTGCTGATATGGCAATCAGACTGGCTAAAGCCTTTGATACCACCATCGAATTCTGGCTGAACCTGCAGCTGAACGTAGAC
ATCTGGGAAGTGCAGACCAACTCACGGACGCAGGAAGAGTTAGGCCGTATCAAGTGCGTTGCGGAGATCCTGGCAAAGAA
AAAGTCTGGCCAGCCGGATGTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References