Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 843720..844300 Replicon chromosome
Accession NZ_CP046444
Organism Granulicella sp. 5B5

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag GOB94_RS03665 Protein ID WP_182277553.1
Coordinates 843720..844013 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag GOB94_RS03670 Protein ID WP_182277554.1
Coordinates 844010..844300 (+) Length 97 a.a.

Genomic Context


GOB94_RS03650GOB94_RS03655GOB94_RS03660GOB94_RS03665GOB94_RS03670GOB94_RS03635GOB94_RS03640GOB94_RS03645GOB94_RS03675GOB94_RS03680GOB94_RS03685
Location: 841676..842182 (507 bp)
Type: Others
Protein ID: WP_182277551.1
Location: 842193..842969 (777 bp)
Type: Others
Protein ID: WP_182277552.1
Location: 843181..843627 (447 bp)
Type: Others
Protein ID: WP_182278413.1
Location: 843720..844013 (294 bp)
Type: Toxin
Protein ID: WP_182277553.1
Location: 844010..844300 (291 bp)
Type: Antitoxin
Protein ID: WP_182277554.1
Location: 839093..840115 (1023 bp)
Type: Others
Protein ID: WP_182278412.1
Location: 840227..841063 (837 bp)
Type: Others
Protein ID: WP_182277549.1
Location: 841125..841526 (402 bp)
Type: Others
Protein ID: WP_182277550.1
Location: 844352..845470 (1119 bp)
Type: Others
Protein ID: WP_182277555.1
Location: 845582..846601 (1020 bp)
Type: Others
Protein ID: WP_182278414.1
Location: 846761..848539 (1779 bp)
Type: Others
Protein ID: WP_182277556.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GOB94_RS03635839093..840115-1023WP_182278412.1sugar kinase-
GOB94_RS03640840227..841063-837WP_182277549.15-dehydro-4-deoxy-D-glucuronate isomerase-
GOB94_RS03645841125..841526-402WP_182277550.1cupin domain-containing protein-
GOB94_RS03650841676..842182+507WP_182277551.1twin-arginine translocation signal domain-containing protein-
GOB94_RS03655842193..842969+777WP_182277552.1glucose 1-dehydrogenase-
GOB94_RS03660843181..843627+447WP_182278413.1hypothetical protein-
GOB94_RS03665843720..844013+294WP_182277553.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GOB94_RS03670844010..844300+291WP_182277554.1putative addiction module antidote proteinAntitoxin
GOB94_RS03675844352..845470-1119WP_182277555.1acyltransferase-
GOB94_RS03680845582..846601-1020WP_182278414.1rod shape-determining protein-
GOB94_RS03685846761..848539-1779WP_182277556.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 10732.44 Da        Isoelectric Point: 10.2588

>T144265 WP_182277553.1 NZ_CP046444:843720-844013 [Granulicella sp. 5B5]
VIEIRETETFAGWLSQLRDDRAKAKIAVRVRRLAFGNPGDIKPVGEGVSELRIPHGPGYRVYFIQRGSLLIVLLCGGDKS
SQNKDIATAKKLAKEEL

Download         Length: 294 bp

>T144265 NZ_CP061801:3539191-3539514 [Enterobacter mori]
ATTTCATCTGTACCGGCCACGGTGCCGGTTTCGTCACGCCTGTCGCCCGTGCAGGTCTGGCAGCAACTGTTGACGTATCT
GCTGGAGCAGCACTACGGCCTGACTCTCAACGACACACCATTTCATGACGACACGGCCATTGAGGAGCATATCGATGCGG
GAATAACGCTTGCCGATGCTGTTAATTTCCTGGTCGAAAAGTACGAACTGGTTCGTATCGATCGGAAGGGATTTTCATGG
CAAGAACAAACCCCGTATATTTCCGTAGTAGATATTTTGCGAGCAAGGCGCTCTACCGGCTTGCTAAAAACTAATGTGAA
ATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 9913.21 Da        Isoelectric Point: 4.5338

>AT144265 WP_182277554.1 NZ_CP046444:844010-844300 [Granulicella sp. 5B5]
MTAAKTKPFDPAAYLDSPEAIATYLTEALETGDPAFVADALGVVARARGMSEVAHAAGVSRESLYRALSAEGNPEFGTVL
KVAQALGVRLAFETAA

Download         Length: 291 bp

>AT144265 NZ_CP061801:3538830-3539153 [Enterobacter mori]
ATGCAAAATTCATGGGGACTGAAGCGCGACATCTCGCCGTGCTTCGGTGCAAGACTTGTGCAGGAAGGCTGTCGCCTGCA
TTTTCTGGCGGACCGTGCGGGTATTAGCGGTACGTTTAACAAGGACGAGGCGCTGCGTCTGGATCAGGCGTTTCCGCTAG
TGATGAAACAGCTTGAATTGATGCTGACAACCGGTGAACTGAATCTGCGCCATCAGCATTGCGTCACGTTGCATCATAAC
GGACTCACCTGCGAGGCTGATACTCTGGGCTCTCACGGCTATGTTTACATCGTTATTTATCCGCAGGCATCTGCAACCCA
GTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References